ดร. เอกลักษณ์ พุกนุ่น
Dr. Aekkalak Puknun
4
ผลงานตีพิมพ์
First: 2
|
Co: 2
70
Citations รวม
4
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รายการผลงานสิ่งตีพิมพ์ (4 รายการ)
Ultrastructural effects and antibiofilm activity of LFchimera against Burkholderia pseudomallei
World Journal of Microbiology and Biotechnology (2016)
ประเทศร่วมวิจัย:
Netherlands, 
Thailand
Netherlands, Thailand
แหล่งทุนวิจัย: Higher Education Research Promotion
บทคัดย่อ (Abstract): Lactoferrin chimera (LFchimera), a hybrid peptide containing the two antimicrobial stretches of the innate immunity factor bovine lactoferrin, viz. LFampin265-284 and LFcin17-30, has strikingly high antimicrobial activity against the category B pathogen Burkholderia pseudomallei. The action mecha...
Drug susceptibility and biofilm formation of burkholderia pseudomallei in nutrient-limited condition
Tropical Biomedicine (2015)
ประเทศร่วมวิจัย:
Thailand
Thailand
บทคัดย่อ (Abstract): Burkholderia pseudomallei is the causative agent of melioidosis, which can form biofilms and microcolonies in vivo and in vitro. One of the hallmark characteristics of the biofilm-forming bacteria is that they can be up to 1,000 times more resistant to antibiotics than their free-living counterpa...
Membrane-active mechanism of LFchimera against Burkholderia pseudomallei and Burkholderia thailandensis
Biometals (2014)
ประเทศร่วมวิจัย:
Netherlands, Thailand
Netherlands, Thailand
แหล่งทุนวิจัย: Higher Education Research Promotion
บทคัดย่อ (Abstract): LFchimera, a construct combining two antimicrobial domains of bovine lactoferrin, lactoferrampin265-284 and lactoferricin17-30, possesses strong bactericidal activity. As yet, no experimental evidence was presented to evaluate the mechanisms of LFchimera against Burkholderia isolates. In this stu...
A heterodimer comprised of two bovine lactoferrin antimicrobial peptides exhibits powerful bactericidal activity against Burkholderia pseudomallei
World Journal of Microbiology and Biotechnology (2013)
ประเทศร่วมวิจัย:
Thailand, Netherlands
Thailand, Netherlands
บทคัดย่อ (Abstract): Melioidosis is a severe infectious disease that is endemic in Southeast Asia and Northern Australia. Burkholderia pseudomallei, the causative agent of this disease, has developed resistance to an increasing list of antibiotics, demanding a search for novel agents. Lactoferricin and lactoferrampin...