ศ.ดร. เสมอ ถาน้อย
Prof. Dr. Samur Thanoi
สาขาการวิจัย:
Neuroscience · 20
Biochemistry, Genetics and Molecular Biology · 19
38
ผลงานตีพิมพ์
First: 12
|
Co: 26
393
Citations รวม
12
h-index
ภาพรวมความเชี่ยวชาญและคุณภาพผลงานวิจัย (Research Highlights & Impact)
คุณภาพวารสาร (Quartiles)
Q1+Q2: 66%
Q1
17
Q2
8
Q3
12
Q4
0
ยึดตาม Scopus CiteScore
ไม่มี Q: 1
SDGs เชี่ยวชาญหลัก
พบ 5 เป้าหมาย
37 เรื่อง
4 เรื่อง
3 เรื่อง
จำแนกตามพจนานุกรมคำสำคัญของคณะ
ดัชนีอ้างอิงสากล (NIH RCR)
NIH iCite Benchmark
RCR เฉลี่ย
0.58
RCR สูงสุด
1.69
อยู่ในเกณฑ์มาตรฐานสากล
เกณฑ์มาตรฐานโลก = 1.00 (NIH Benchmark)
เครือข่ายสากล & หัวข้อวิจัย
ประเทศร่วมวิจัยหลัก:
United Kingdom (17)
หัวข้อวิจัยเด่น (OpenAlex):
การวิเคราะห์คลัสเตอร์สากล (OpenAlex Topics)
รายการผลงานสิ่งตีพิมพ์ (38 รายการ)
Protective Effect of Pre-Germinated Brown Rice on Withdrawal Symptoms and Glutamate N-Methyl-D-Aspartate Receptor Subunit 1 Expression in Hippocampus in A Rat Model of Drug Withdrawal
Trends in Sciences (2026)
ประเทศร่วมวิจัย:
Thailand, United Kingdom
Thailand, United Kingdom
แหล่งทุนวิจัย: Agricultural Research Development Agency (PRP5605021870)
บทคัดย่อ (Abstract): Drug withdrawal is recognized as a global health issue. Abuse of dextromethorphan (DXM), an over-the-counter antitussive, leads to addiction and withdrawal symptoms by acting on glutamate N-methyl-D-aspartate (NMDA) receptors. Nonetheless, effective agents for alleviating withdrawal symptoms rema...
Differential protein expression profiles in human sperm from teratozoospermic and normozoospermic men identify LTBP1 and TGF-βR1 as potential biomarkers within the TGF-β signalling pathway
Plos One (2026)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Naresuan University (R2567C018)
บทคัดย่อ (Abstract): Among cases of infertility, up to 50% are attributed to male infertility factors. Male infertility is associated with alterations in sperm proteins that are essential for normal sperm function. Alterations in proteins within the transforming growth factor-beta (TGF-β) signalling pathway are linke...
Proteomic associations with cognitive variability as measured by the Wisconsin Card Sorting Test in a healthy Thai population: A machine learning approach
Plos One (2025)
ประเทศร่วมวิจัย:
United Kingdom, Thailand
United Kingdom, Thailand
แหล่งทุนวิจัย: Naresuan University (R2567C003)
บทคัดย่อ (Abstract): Inter-individual cognitive variability, influenced by genetic and environmental factors, is crucial for understanding typical cognition and identifying early cognitive disorders. This study investigated the association between serum protein expression profiles and cognitive variability in a healt...
Regional-specific changes in rat brain BDNF in a model of methamphetamine abuse
Neuroscience Letters (2024)
ประเทศร่วมวิจัย:
United Kingdom, Thailand
United Kingdom, Thailand
แหล่งทุนวิจัย: Faculty of Allied Health Sciences, Chulalongkorn University (R2566A044)
บทคัดย่อ (Abstract): Brain-derived neurotrophic factor (BDNF), a member of the neurotrophin family, plays key roles in neuronal protection and synaptic plasticity. Changes in BDNF are associated with various pathological conditions, including methamphetamine (meth) addiction, although the effects of meth on BDNF expr...
A solid lipid particle formulation of long pepper extract reduces pain and astrocyte activation in a rat model of neuropathic pain
Journal of Complementary and Integrative Medicine (2023)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Naresuan University (R2557B007)
บทคัดย่อ (Abstract): Objectives: To investigate the effects of solid lipid microparticle (SLM) creams containing a long pepper extract (LPE) or piperine on neuropathy-related pain and the expression of glial fibrillary acidic protein (GFAP) as a measure of astrogliosis. Methods: Neuropathic pain in male Spraque Dawle...
Proteomic association with age-dependent sex differences in Wisconsin Card Sorting Test performance in healthy Thai subjects
Scientific Reports (2023)
ประเทศร่วมวิจัย:
United Kingdom, Thailand
United Kingdom, Thailand
บทคัดย่อ (Abstract): Sex differences in cognitive function exist, but they are not stable and undergo dynamic change during the lifespan. However, our understanding of how sex-related neural information transmission evolves with age is still in its infancy. This study utilized the Wisconsin Card Sorting Test (WCST) a...
Cholinergic-estrogen interaction is associated with the effect of education on attenuating cognitive sex differences in a Thai healthy population
Plos One (2023)
ประเทศร่วมวิจัย:
United Kingdom, Thailand
United Kingdom, Thailand
แหล่งทุนวิจัย: Ministry of Higher Education, Science, Research and Innovation, Thailand (R2566A044)
บทคัดย่อ (Abstract): The development of human brain is shaped by both genetic and environmental factors. Sex differences in cognitive function have been found in humans as a result of sexual dimorphism in neural information transmission. Numerous studies have reported the positive effects of education on cognitive fu...
Differential protein expression of GABA A receptor alpha 1 subunit and calbindin in rat spermatozoa associated with proteomic analysis in testis following methamphetamine administration
Plos One (2023)
ประเทศร่วมวิจัย:
Thailand
Thailand
บทคัดย่อ (Abstract): Methamphetamine (METH) can induce spermatogenesis impairment, testicular apoptosis, and abnormal sperm quality. It also promotes changes in the expression of receptors for sex hormones and neurotransmitters, including GABA receptors in the testis. Proteomic assessment focusing on proteins involve...
Changes of fsh and lh receptors expressions in rat testis after methamphetamine exposure
Songklanakarin Journal of Science and Technology (2021)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Thailand Research Fund
บทคัดย่อ (Abstract): Methamphetamine (METH), the most widely used psychostimulant in Thailand, has been reported to have harmful effects on testicular functions and sperm quality, but its mechanisms are still unclear. Since follicle‒stimulating hormone (FSH) and luteinizing hormone (LH) play important roles in sperma...
Changes of exon IV DNA methylation are associated with methamphetamine dependence
Epigenomics (2021)
ประเทศร่วมวิจัย:
United Kingdom, Thailand
United Kingdom, Thailand
แหล่งทุนวิจัย: British Council (PHD/0247/2553)
บทคัดย่อ (Abstract): Aim: We investigated DNA methylation of BDNF in methamphetamine (METH) dependence in humans and an animal model. Materials & methods: BDNF methylation at exon IV was determined by pyrosequencing of blood DNA from METH-dependent and control subjects, and from rat brain following an escalating dose...
High mRNA expression of GABA receptors in human sperm with oligoasthenoteratozoospermia and teratozoospermia and its association with sperm parameters and intracytoplasmic sperm injection outcomes
Clinical and Experimental Reproductive Medicine (2021)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Thailand Research Fund
บทคัดย่อ (Abstract): This study investigated the mRNA expression of gamma-aminobutyric acid (GABA) receptors in the sperm of oligoasthenoteratozoospermic (OAT) and teratozoospermic (TER) men compared to normozoospermic (NOR) men, as well as the relationships between GABA receptor expression and sperm parameters, fert...
Pharmacogenetics of drug dependence: Polymorphisms of genes involved in glutamate neurotransmission
Neuroscience Letters (2020)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Office of the Higher Education Commission (R2560B053)
บทคัดย่อ (Abstract): Multiple studies provide evidence to support dysfunction of glutamate neurotransmission in the pathogenesis of drug dependence. Pharmacogenetic investigation of glutamate-related genes has provided further support for the involvement of this neurotransmitter in the risk of, and consequences of, d...
Pharmacogenetics of drug dependence: Polymorphisms of genes involved in GABA neurotransmission
Neuroscience Letters (2020)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: National Research Council of Thailand (PhD 0368/2551)
บทคัดย่อ (Abstract): GABA plays a critical role in brain reward pathways via projecting signals from the ventral tegmental area to the nucleus accumbens. Activation of the reward circuitry by abused drugs induces abnormalities of GABA neurotransmission. Recent studies have indicated the involvement of GABAergic genes...
Changes of dopamine d2, alpha1 adrenergic receptor expressions and developmental stages of seminiferous tubule in rat testis after methamphetamine administration: A preliminary study
Songklanakarin Journal of Science and Technology (2020)
ประเทศร่วมวิจัย:
Thailand
Thailand
บทคัดย่อ (Abstract): The alterations of dopamine D2 receptor (D2R) and α1 adrenergic receptor (α1AR) expressions and developmental stages of seminiferous tubule were investigated in twenty-two male rats that underwent one of three Methamphetamine (METH) treatment regimes: acute binge (AB), escalating dose (ED) or esc...
Changes in sperm quality and testicular structure in a rat model of type 1 diabetes
Asian Biomedicine (2019)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Naresuan University (AAT41)
บทคัดย่อ (Abstract): Chronic hyperglycemia is a characteristic of diabetes mellitus (DM). Long-lasting hyperglycemia can generate oxidative stress and reactive oxygen species. The effect of this condition on sperm quality and spermatogenesis leads to male infertility and reproductive dysfunction. To investigate chang...
Association of SLC1A2 and SLC17A7 polymorphisms with major depressive disorder in a Thai population
Asian Biomedicine (2019)
ประเทศร่วมวิจัย:
United Kingdom, Thailand
United Kingdom, Thailand
แหล่งทุนวิจัย: Office of the Higher Education Commission (AAT41)
บทคัดย่อ (Abstract): Major depressive disorder (MDD) is a common psychiatric disorder with high prevalence and high risk of suicide. Genetic variation of glutamate transporters may associate with MDD and suicide attempt. To evaluate polymorphisms of excitatory amino acid transporter 2 gene (SLC1A2; rs752949, rs188534...
Association study of the functional Catechol-OMethyltranferase (COMT) Val158Met polymorphism on executive cognitive function in a Thai sample
International Journal of Medical Sciences (2019)
ประเทศร่วมวิจัย:
United Kingdom, Thailand
United Kingdom, Thailand
แหล่งทุนวิจัย: National Research Council of Thailand
บทคัดย่อ (Abstract): Catechol-O-Methyltranferase (COMT) plays a crucial role in the removal of cortical dopamine and is strongly implicated in human executive function. Numerous studies have reported associations of the COMT Val158Met (rs4680) polymorphism with executive function in healthy subjects. However, little ...
Parvalbumin promoter methylation altered in major depressive disorder
International Journal of Medical Sciences (2019)
ประเทศร่วมวิจัย:
United Kingdom, Thailand
United Kingdom, Thailand
แหล่งทุนวิจัย: British Council (2015/16)
บทคัดย่อ (Abstract): Aims: To determine the extent of DNA methylation of parvalbumin gene (PVALB) promoter in major depressive disorder (MDD) patients with and without suicide attempt in comparison with healthy controls. Methods: The extracted DNA from dried blood spots of MDD patients (n = 92) including non-suicidal...
Gabaergic alterations in the rat testis after methamphetamine exposure
International Journal of Medical Sciences (2018)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Thailand Research Fund
บทคัดย่อ (Abstract): Gamma-aminobutyric acid (GABA), GABA-A receptors and GABA transporter 1 (GAT1) were reported to be involved in the proliferation of Leydig cells, testosterone production and spermatogenesis. Since methamphetamine (METH) has been reported to have adverse effects on testis and its functions, the ai...
Recovery effect of pre-germinated brown rice on the changes of sperm quality, testicular structure and androgen receptor expression in a rat model of drug addiction
International Journal of Medical Sciences (2018)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Agricultural Research Development Agency
บทคัดย่อ (Abstract): Drug addiction is reported to have adverse effects in male reproduction. Dextromethorphan (DXM) administration was used in this study as a model of addiction in rats, and various treatments including the use of pre-germinated brown rice (PGBR) were investigated for their effects on the changes of...
Genetic variation of GRIA3 gene is associated with vulnerability to methamphetamine dependence and its associated psychosis
Journal of Psychopharmacology (2018)
ประเทศร่วมวิจัย:
United Kingdom, Thailand
United Kingdom, Thailand
แหล่งทุนวิจัย: Ministry of Justice (PHD/0247/2553)
บทคัดย่อ (Abstract): Methamphetamine (METH) is an addictive psychostimulant drug commonly leading to schizophrenia-like psychotic symptoms. Disturbances in glutamatergic neurotransmission have been proposed as neurobiological mechanisms and the α-amino-3 hydroxy-5 methyl-4 isoxazole propionic acid (AMPA) glutamate re...
Increased DNA methylation in the parvalbumin gene promoter is associated with methamphetamine dependence
Pharmacogenomics (2017)
ประเทศร่วมวิจัย:
United Kingdom, Thailand
United Kingdom, Thailand
บทคัดย่อ (Abstract): Aim: The parvalbumin (PV)-containing subgroup of GABAergic neurons is particularly affected in schizophrenia and animal models of psychosis, including after methamphetamine (METH) administration. We investigated whether METH dependence and METH-induced psychosis may involve an effect on DNA methy...
Alteration of catecholamine concentrations in rat testis after methamphetamine exposure
Andrologia (2017)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Naresuan University
บทคัดย่อ (Abstract): Methamphetamine (METH) is an illicit drug that can lead to changes in catecholamines in the brain. It also has substantial effects on reproductive function. We investigated whether rat models of METH abuse could induce changes in the dopamine metabolite 3,4-dihydroxyphenylacetic acid (DOPAC), nor...
Recovery effect of pre-germinated brown rice on the alteration of sperm quality, testicular structure and androgen receptor expression in rat model of depression
Andrologia (2017)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Naresuan University
บทคัดย่อ (Abstract): Depression and antidepressant drugs induce adverse effects in male reproduction. Therefore, it is important to investigate alternative treatment for depression without adverse effects on the male reproductive system. The aim of this study was to determine the effect of pre-germinated brown rice (...
Association of polymorphisms in GAD1 and GAD2 genes with methamphetamine dependence
Pharmacogenomics (2017)
ประเทศร่วมวิจัย:
United Kingdom, Thailand
United Kingdom, Thailand
บทคัดย่อ (Abstract): Aim: Association between polymorphisms in GAD genes and methamphetamine (METH) dependence was investigated in the Thai population. Materials & methods: Genotypes of rs769404 and rs701492 in GAD1 and rs2236418 in GAD2 polymorphisms were determined in 100 METH-dependent male subjects and 102 matche...
Effect of Methamphetamine Exposure on Expression of Calcium Binding Proteins in Rat Frontal Cortex and Hippocampus
Neurotoxicity Research (2016)
ประเทศร่วมวิจัย:
United Kingdom, Thailand
United Kingdom, Thailand
แหล่งทุนวิจัย: Thailand Research Fund (PHD/0368/2551)
บทคัดย่อ (Abstract): Methamphetamine (METH) is a psychostimulant drug with potent effects on the central nervous system that can cause psychotic symptoms similar to those of schizophrenia. Specific alterations in GABAergic neuronal markers have been reported in schizophrenia and animal models of psychotic illness. Th...
Changes of sperm quality and hormone receptors in the rat testis after exposure to methamphetamine
Drug and Chemical Toxicology (2016)
ประเทศร่วมวิจัย:
Thailand
Thailand
บทคัดย่อ (Abstract): Methamphetamine (METH) is known to damage neurons and induce psychosis. It can also induce apoptosis in seminiferous tubules and affect sperm quality. The present study was carried out to investigate the effect of a rat model of METH addiction on sperm quality and expression of progesterone recep...
Changes of androgen receptor expression in stages VII-VIII seminiferous tubules of rat testis after exposure to methamphetamine
Songklanakarin Journal of Science and Technology (2016)
ประเทศร่วมวิจัย:
Thailand
Thailand
บทคัดย่อ (Abstract): Methamphetamine (METH) is toxic not only to the central nervous system but also to the reproductive system. This study aimed to investigate the effect of METH administration on androgen receptor (AR) expression in the seminiferous tubules (stages VII-VIII) and Leydig cells. 24 Sprague-Dawley rats...
Does elevated peripheral benzodiazepine receptor gene expression relate to cognitive deficits in methamphetamine dependence?
Human Psychopharmacology (2016)
ประเทศร่วมวิจัย:
United Kingdom, Thailand
United Kingdom, Thailand
บทคัดย่อ (Abstract): Background Methamphetamine (METH) is a neurotoxin and psychostimulant drug with potent effects on the central nervous system. With chronic METH administration, an inflammatory glial response is observed as a result of METH-induced neurotoxicity. One inflammatory marker is the peripheral benzodiaz...
BDNF (Val66Met) genetic polymorphism is associated with vulnerability for methamphetamine dependence
Pharmacogenomics (2015)
ประเทศร่วมวิจัย:
United Kingdom, Thailand
United Kingdom, Thailand
บทคัดย่อ (Abstract): Aim: Association of the brain-derived neurotrophic factor (BDNF) genetic polymorphism rs6265 (Val66Met) with methamphetamine (METH) dependence and METH-induced psychosis was investigated in the Thai population. Materials & methods: The rs6265 genotype was determined in 100 male METH-dependent sub...
Genetic variation of GRIN1 confers vulnerability to methamphetamine-dependent psychosis in a Thai population
Neuroscience Letters (2013)
ประเทศร่วมวิจัย:
United Kingdom, Thailand
United Kingdom, Thailand
แหล่งทุนวิจัย: Office of the Higher Education Commission
บทคัดย่อ (Abstract): GRIN1 is a gene that encodes the N-methyl-. d aspartate (NMDA) receptor subunit1 (NR1). Variations of GRIN1 have been identified as a risk factor for schizophrenia and drug dependence, supporting hypotheses of glutamatergic dysfunction in these disorders. Methamphetamine (METH) is a psychostimula...
Changes in the Neuronal Glutamate Transporter EAAT3 in Rat Brain after Exposure to Methamphetamine
Basic and Clinical Pharmacology and Toxicology (2012)
ประเทศร่วมวิจัย:
Thailand
Thailand
บทคัดย่อ (Abstract): Methamphetamine (METH), an addictive psychostimulant, can induce glutamate release in several brain areas such as cerebral cortex, hippocampus and striatum. Excess glutamate is ordinarily removed from the synaptic cleft by glutamate transporters for maintaining homoeostasis. EAAT3, a subtype of g...
An association between genotypic variations and protein expression of the glial glutamate transporter 2 in the human nucleus accumbens
Neuroscience Letters (2012)
ประเทศร่วมวิจัย:
United Kingdom, Thailand
United Kingdom, Thailand
แหล่งทุนวิจัย: British Council
บทคัดย่อ (Abstract): The glial glutamate transporter EAAT2 is responsible for the majority of synaptic glutamate clearance. Dysfunction of EAAT2 is strongly implicated in neuropsychiatric disorders. Single nucleotide polymorphisms (SNPs) in the EAAT2 gene have been associated with an increased risk of pathological co...
Pseudoephedrine induces sperm abnormalities, lower sperm counts and increased apoptosis in rat testis
Cell and Tissue Research (2012)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Office of the Higher Education Commission
บทคัดย่อ (Abstract): Pseudoephedrine, an over-the-counter drug, is commonly used for the treatments of asthma, nasal congestion, and obesity. Furthermore, it can be used as a psychostimulant drug if taken in large doses; however, there have been no reports on its effects on reproduction. The aim of this study was the...
Methamphetamine induces abnormal sperm morphology, low sperm concentration and apoptosis in the testis of male rats
Andrologia (2011)
ประเทศร่วมวิจัย:
Thailand
Thailand
บทคัดย่อ (Abstract): Methamphetamine has been reported to be an important drug in the field of reproductive toxicology. The aim of this study was to investigate the effects of methamphetamine administrations on sperm morphology, sperm concentration and apoptotic activity inside seminiferous tubule in male rats. Rats ...
Changes in glutamate/NMDA receptor subunit 1 expression in rat brain after acute and subacute exposure to methamphetamine
Journal of Biomedicine and Biotechnology (2009)
ประเทศร่วมวิจัย:
Thailand
Thailand
บทคัดย่อ (Abstract): Methamphetamine (METH) is a psychostimulant drug of abuse that produces long-term behavioral changes including behavioral sensitization, tolerance, and dependence. METH has been reported to induce neurotoxic effects in several areas of the brain via the dopaminergic system. Changes of dopamine fu...
A comparison of degree of cortical granule exocytosis in zona-free pig oocytes induced by different artificial stimulators
Scienceasia (2007)
ประเทศร่วมวิจัย:
Thailand
Thailand
บทคัดย่อ (Abstract): Cortical granule (CG) exocytosis occurs when the first sperm fertilizes an oocyte to modify the extracellular environment and zona pellucida of the oocyte thereby preventing polyspermy. Apart from sperm penetration, many artificial stimulators have been reported to induce CG exocytosis in mammali...
Increase of glutamate/N-methyl-d-aspartate receptor immunodensity in the dentate gyrus of rats following pseudoephedrine administration
Neurotoxicology (2006)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Thailand Research Fund
บทคัดย่อ (Abstract): Pseudoephedrine is a sympathomimetic drug in which its structure is similar to amphetamine. Although pseudoephedrine is not as potent as amphetamine, it has been reported that the actions of pseudoephedrine on the central nervous system via dopamine release resemble to amphetamine. Changes of dop...