รศ.ดร. อาทิตย์ ทิมอ่วม
Assoc.Prof.Dr. Arthid Thimuam
สาขาการวิจัย:
Medicine · 26
Biochemistry, Genetics and Molecular Biology · 19
36
ผลงานตีพิมพ์
First: 0
|
Co: 36
599
Citations รวม
14
h-index
ภาพรวมความเชี่ยวชาญและคุณภาพผลงานวิจัย (Research Highlights & Impact)
คุณภาพวารสาร (Quartiles)
Q1+Q2: 100%
Q1
26
Q2
10
Q3
0
Q4
0
ยึดตาม Scopus CiteScore
SDGs เชี่ยวชาญหลัก
พบ 4 เป้าหมาย
35 เรื่อง
8 เรื่อง
6 เรื่อง
จำแนกตามพจนานุกรมคำสำคัญของคณะ
ดัชนีอ้างอิงสากล (NIH RCR)
NIH iCite Benchmark
RCR เฉลี่ย
1.72
RCR สูงสุด
5.31
ได้รับการอ้างอิงสูงกว่าเกณฑ์เฉลี่ยโลก
เกณฑ์มาตรฐานโลก = 1.00 (NIH Benchmark)
เครือข่ายสากล & หัวข้อวิจัย
ประเทศร่วมวิจัยหลัก:
Australia (4)
United States (4)
Japan (2)
หัวข้อวิจัยเด่น (OpenAlex):
การวิเคราะห์คลัสเตอร์สากล (OpenAlex Topics)
รายการผลงานสิ่งตีพิมพ์ (36 รายการ)
Phytochemical profiling of Syzygium nervosum fruit pulp extracts and their modulatory effects on oxidative stress and cytokine production
BMC Complementary Medicine and Therapies (2026)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: School of Medical Sciences, Universiti Sains Malaysia (RSPG670029)
บทคัดย่อ (Abstract): Syzygium nervosum A. Cunn. ex DC., a plant traditionally used in Southeast Asian medicine, has recently gained scientific attention for its broad range of biological activities and health benefits, including anti-inflammatory, antimicrobial, and antitumor effects. In this study, we aim to compare...
Protective effects of ethanolic lychee (Litchi chinensis Sonn.) seed extract against adipogenesis and inflammation in 3T3-L1 cells
Molecular Biology Reports (2026)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: University of Phayao (RSPG670031)
บทคัดย่อ (Abstract): Background: In light of the critical role of adipogenesis and inflammation in the development of obesity, various plant-derived extracts have been reported to attenuate the differentiation of preadipocytes into mature adipocytes. This study elucidated the protective effect of ethanolic lychee see...
Fine Particulate Matter (PM2.5), the Exposome, and Cumulative Health Risk: A Life-course Perspective
Journal of Preventive Medicine and Public Health (2026)
ประเทศร่วมวิจัย:
Japan, Thailand
Japan, Thailand
บทคัดย่อ (Abstract): Article
Intratracheal Candida administration induced lung dysbiosis, activated neutrophils, and worsened lung hemorrhage in pristane-induced lupus mice
Scientific Reports (2025)
ประเทศร่วมวิจัย:
United Kingdom, Thailand, Australia, Japan
United Kingdom, Thailand, Australia, Japan
แหล่งทุนวิจัย: University of Phayao (MS 251001)
บทคัดย่อ (Abstract): Because the innate immunity might and fungi in the lungs might enhance the severity of lupus-induced diffuse alveolar hemorrhage (DAH), intraperitoneal pristane injection was performed in C57BL6 mice with intratracheal administration by Candida albicans or phosphate buffer solution (PBS). Despite...
Accelerating and protective effects toward cancer growth in cGAS and FcgRIIb deficient mice, respectively, an impact of macrophage polarization
Inflammation Research (2025)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: University of Phayao (N42A680423)
บทคัดย่อ (Abstract): Background: Due to the possible influence of inflammation and gut microbiota in cancers. Methods: Fc gamma receptor IIb deficient (FcGRIIb−/−) and cyclic GMP-AMP synthase deficient (cGAS−/−) mice, the model with hyperinflammation and hypo-inflammation, respectively, were subcutaneously injected w...
Genetic and transcriptomic alterations underlying aggressiveness in 5-fluorouracil-resistant HCT116 cells
Medical Oncology (2025)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Thailand Science Research and Innovation (MD66-03)
บทคัดย่อ (Abstract): Resistance to 5-fluorouracil (5-FU) remains an obstacle to effective colorectal cancer (CRC) treatment. Genetic alterations play significant roles in the development of drug-induced chemoresistance, leading to tumor recurrence and increased aggressiveness. This study sought to characterize the tr...
Less severe tumor growth in mice in which mgmt is conditionally deleted using the LysM-Cre system, and the possible impacts of DNA methylation in tumor-associated macrophages
International Immunology (2025)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: National Research Council of Thailand (N42A680423)
บทคัดย่อ (Abstract): Despite the importance of o6-methylguanine-DNA methyltransferase (MGMT) (a DNA repair enzyme) in cancer cells, the impacts of MGMT in macrophages are still unknown. In mgmt null mice (mgmtflox/flox; LysM-Crecre/-; mgmt deletion only in macrophages), subcutaneous administration of MC38 (a murine c...
Anti-inflammatory effects and gut microbiota modulation of synbiotic mulberry in DSS-induced colitis rats
Molecular and Cellular Biochemistry (2025)
ประเทศร่วมวิจัย:
Thailand
Thailand
บทคัดย่อ (Abstract): The global incident shows that the number of inflammatory bowel disease (IBD) cases increased by 88.30% in 2021 and significantly influenced patients' quality of life. Synbiotics are recommended as an alternative or supplement for IBD. We formulated synbiotic mulberry (SM) by mixing mulberry powd...
Hibiscus sabdariffa L. (Roselle flower) extract exerts protective effects against lipopolysaccharide-induced inflammation by ameliorating TLR4/NF-κB and NLRP3 inflammasome activation
Inflammopharmacology (2025)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Thailand Science Research and Innovation (FF66-RIM061)
บทคัดย่อ (Abstract): The phytochemical constituents of various plant extracts have shown potential in mitigating oxidative stress and inflammation. Hibiscus sabdariffa L. (HS), known as the roselle flower, has demonstrated antioxidant and anti-inflammatory effects in several models. Our study aimed to evaluate the ef...
Red Onion Peels Extract: A Food Waste for Silver Nanoparticles Synthesis and Potential Application in Air Cleaning Devices
Chiang Mai Journal of Science (2025)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: University of Phayao (FF67-242/2567)
บทคัดย่อ (Abstract): Red Onion (Allium cepa L.) Peels (ROP) is an unwanted agricultural byproduct after cooking but it is rich with bioactive compounds such as phenolics, flavonoids, flavanols and quercetin. In this work, we employed the extract of ROP as a reducing agent in green synthesis of silver nanoparticles (A...
Anthocyanins from a new hybrid sweet potato peel cultivated in Northern Thailand mitigate LPS-induced inflammation and RANKL-induced osteoporosis by regulating ROS-mediated pathways
Inflammopharmacology (2025)
ประเทศร่วมวิจัย:
Thailand, 
South Korea
Thailand, South Korea
แหล่งทุนวิจัย: University of Phayao (FF66-RIM063)
บทคัดย่อ (Abstract): Maejo 341 Sweet potato (MSP) is a new purple sweet potato variety cultivated in Northern Thailand, but its health benefits are unknown. This study aimed to investigate its antioxidant, anti-inflammatory, and anti-osteoporotic activities, as well as its anthocyanin content. The peel and flesh of M...
Phytochemical Screening and In Vitro Antioxidant and Anticancer Evaluation of Stem and Leaf Extracts of Cissampelos pareira L.
Mediators of Inflammation (2025)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: University of Phayao (253/2567)
บทคัดย่อ (Abstract): This study was conducted to investigate the phytochemical constituents, antioxidant capacity, and anticancer potential of aqueous, ethanolic, and hexane extracts derived from the leaves and stems of Cissampelos pareira L. (C. pareira L.). Proximate analysis revealed that the stems contained a hig...
Elaeagnus latifolia Fruit Extract Ameliorates High-Fat Diet-Induced Obesity in Mice and Alleviates Macrophage-Induced Inflammation in Adipocytes In Vitro
Antioxidants (2024)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: University of Phayao (RGNS 65-137)
บทคัดย่อ (Abstract): Elaeagnus latifolia (EL) is a wild fruit known for containing several health-promoting compounds. This study aimed to evaluate the effects of EL fruit extract on high-fat diet (HFD)-induced obesity and lipopolysaccharide (LPS)-activated macrophages. Mice fed an HFD and given EL fruit extract for ...
A randomized controlled clinical trial examining the effects of Cordyceps militaris beverage on the immune response in healthy adults
Scientific Reports (2024)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Agência Nacional de Inovação (PE0201-02-64-09-0208)
บทคัดย่อ (Abstract): Cordyceps militaris (L.) Link (C. militaris) contains various beneficial substances, including polysaccharides (galactomannan), nucleotides (adenosine and cordycepin), cordycepic acid, amino acids, and sterols (ergosterol and beta-sitosterol). It also contains other essential nutrients, such as p...
Subchronic oral toxicity study of the synbiotic mulberry in male and female Wistar rats
Food and Chemical Toxicology (2024)
ประเทศร่วมวิจัย:
Thailand
Thailand
บทคัดย่อ (Abstract): Mulberry (Morus alba L) fruit is traditionally used in Chinese medicine and has several beneficial effects, such as hypoglycemic, hypolipidemic, and anti-oxidative effects. We previously developed the synbiotic mulberry (SM) containing probiotic Lactobacilli, prebiotic inulin, and mulberry powder...
Red rice bran aqueous extract ameliorate diabetic status by inhibiting intestinal glucose transport in high fat diet/STZ-induced diabetic rats
Journal of Traditional and Complementary Medicine (2024)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Office of National Higher Education Science Research and Innovation Policy Council (FF64-RIB008)
บทคัดย่อ (Abstract): Red rice (Oryza sativa L.) consumption has grown recently, partly due to its potential health benefits in several disease prevention. The impact of red rice bran aqueous extract (RRBE) on intestinal glucose uptake and diabetes mellitus (DM) progression has not been thoroughly investigated. This s...
Hepatoprotective effects of Elaeagnus latifolia fruit extract against acetaminophen-induced hepatotoxicity in mice: Mechanistic insights
Journal of Functional Foods (2024)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Thammasat University (FF64-RIB009)
บทคัดย่อ (Abstract): Elaeagnus latifolia fruit extract (EE) has been reported to contain antioxidant and anti-inflammatory phytochemicals. The present study aimed to examine the anti-hepatotoxic effects of EE in acetaminophen (APAP)-injected mice. Pretreatment with EE for 7 days in APAP mice showed significant reduct...
Cotton tree (Bombax ceiba L.) flower stamen extract: Turning a food ingredient into a reducing agent for the green synthesis of silver nanoparticles
Scienceasia (2024)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Thailand Science Research and Innovation (FF65-RIM068)
บทคัดย่อ (Abstract): Cotton tree (Bombax ceiba L.) flower stamen has been used widely as a northern Thai food ingredient.In this work, microwave extraction was applied to obtain the Bombax ceiba L. (BOMBAX) flower stamen extract foruse as a reducing agent in the green synthesis of silver nanoparticles (AgNPs). The co...
Effects of Pogonatherum paniceum (Lamk) Hack extract on anti-mitochondrial DNA mediated inflammation by attenuating Tlr9 expression in LPS-induced macrophages
Nutrition Research and Practice (2023)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: University of Phayao (RD61067)
บทคัดย่อ (Abstract): BACKGROUND/OBJECTIVES: Mitochondrial DNA leakage leads to inflammatory responses via endosome activation. This study aims to evaluate whether the perennial grass water extract (Pogonatherum panicum) ameliorate mitochondrial DNA (mtDNA) leakage. MATERIALS/METHODS: The major bioactive constituents ...
Synergistic Effects of Azithromycin and STING Agonist Promote IFN-I Production by Enhancing the Activation of STING-TBK1 Signaling
Journal of Experimental Pharmacology (2023)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: University of Phayao (FF65-RIM104)
บทคัดย่อ (Abstract): Background: Azithromycin (AZM) is a macrolide antibiotic that exhibits anti-inflammatory and anti-viral infection properties by enhancing type-I interferon (IFN-I) responses. The stimulator of interferon genes (STING) can directly induce IFN-I production. However, elevated IFN-I induces auto-immu...
cGAS deficiency enhances inflammasome activation in macrophages and inflammatory pathology in pristane-induced lupus
Frontiers in Immunology (2022)
ประเทศร่วมวิจัย:
Thailand, United States
Thailand, United States
แหล่งทุนวิจัย: Chulalongkorn University (FRB65_hea (44)_051_30_32.)
บทคัดย่อ (Abstract): Introduction: Type I interferon (IFN) plays a vital role in the pathogenesis of systemic lupus erythematosus. Cyclic GMP AMP synthase (cGAS) is a cytosolic DNA sensor that recognizes dsDNA and creates cGAMP to activate STING-mediated type I IFN production. The activation of STING induces lupus di...
Anti‐Inflammatory Effects of Red Rice Bran Extract Ameliorate Type I Interferon Production via STING Pathway
Foods (2022)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Otago School of Medical Sciences (FF64‐ RIM039)
บทคัดย่อ (Abstract): Type I interferons (IFNs‐I) are inflammatory cytokines that play an essential role in the pathogenesis of inflammation and autoimmune diseases. Signaling through nucleic acid sensors causes the production of IFNs‐I. A stimulator of interferon genes (STING) is a DNA sensor that signals transductio...
Effects of Red Rice Bran Extract on High-Fat Diet-Induced Obesity and Insulin Resistance in Mice
Preventive Nutrition and Food Science (2022)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: University of Phayao (FF64-RIB008)
บทคัดย่อ (Abstract): Insulin resistance is a salient player in the pathogenesis of obesity and its related abnormal glucose-insulin homeostasis. Red rice bran extract (RRBE) demonstrates several bioactive phytochemicals with anti-diabetic properties. However, little is known about its molecular mechanisms. Therefore,...
Enhanced Bacteremia in Dextran Sulfate‐Induced Colitis in Splenectomy Mice Correlates with Gut Dysbiosis and LPS Tolerance
International Journal of Molecular Sciences (2022)
ประเทศร่วมวิจัย:
Thailand, Australia
Thailand, Australia
แหล่งทุนวิจัย: Chulalongkorn University (IRN59W0004)
บทคัดย่อ (Abstract): Because both endotoxemia and gut dysbiosis post‐splenectomy might be associated with systemic infection, the susceptibility against infection was tested by dextran sulfate solution (DSS)‐ induced colitis and lipopolysaccharide (LPS) injection models in splenectomy mice with macrophage experiments...
Increased susceptibility to dextran sulfate-induced mucositis of iron-overload β-thalassemia mice, another endogenous cause of septicemia in thalassemia
Clinical Science (2021)
ประเทศร่วมวิจัย:
Thailand, Australia
Thailand, Australia
แหล่งทุนวิจัย: Chulalongkorn University (B05F630073)
บทคัดย่อ (Abstract): Enterocyte damage and gut dysbiosis are caused by iron-overload in thalassemia (Thl), possiblymaking the gut vulnerable to additional injury. Hence, iron-overload in the heterozygous β-globin deficient (Hbbth3/+) mice were tested with 3% dextran sulfate solution (DSS). With 4 months of iron-gavag...
Candida administration worsens uremia-induced gut leakage in bilateral nephrectomy mice, an impact of gut fungi and organismal molecules in Uremia
Msystems (2021)
ประเทศร่วมวิจัย:
Thailand, Australia
Thailand, Australia
แหล่งทุนวิจัย: Chulalongkorn University (B05F630073)
บทคัดย่อ (Abstract): The impact of gut fungi and (1→3)-b-D-glucan (BG), a major fungal cell wall component, on uremia was explored by Candida albicans oral administration in bilateral nephrectomy (BiNx) mice because of the prominence of C. albicans in the human intestine but not in mice. As such, BiNx with Candida ad...
A Comparison Between 1 Day versus 7 Days of Sepsis in Mice with the Experiments on LPS-Activated Macrophages Support the Use of Intravenous Immunoglobulin for Sepsis Attenuation
Journal of Inflammation Research (2021)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Chulalongkorn University (IRN59W0004)
บทคัดย่อ (Abstract): Background: Because survival and death after sepsis are partly due to a proper immune adaptation and immune dysregulation, respectively, survivors and moribund mice after cecal ligation and puncture (CLP) sepsis surgery and in vitro macrophage experiments were explored. Methods: Characteristics o...
Leaky-gut enhanced lupus progression in the Fc gamma receptor-IIb deficient and pristane-induced mouse models of lupus
Scientific Reports (2020)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Chulalongkorn University (760001-HR)
บทคัดย่อ (Abstract): The influence of gut-leakage or gut-microbiota upon lupus progression was explored in 2 lupus mouse models. Pristane, administered in 4-wk-old wild-type (WT) female mice, induced lupus characteristics at 24-wk-old similar to the lupus-onset in FcGRIIb−/− mice. Gut-microbiota alteration was induce...
Erratum: STING Mediates Lupus via the Activation of Conventional Dendritic Cell Maturation and Plasmacytoid Dendritic Cell Differentiation (iScience (2020) 23(9), (S2589004220307227), (10.1016/j.isci.2020.101530))
Iscience (2020)
ประเทศร่วมวิจัย:
Thailand
Thailand
บทคัดย่อ (Abstract): [This corrects the article DOI: 10.1016/j.isci.2020.101530.].
STING Mediates Lupus via the Activation of Conventional Dendritic Cell Maturation and Plasmacytoid Dendritic Cell Differentiation
Iscience (2020)
ประเทศร่วมวิจัย:
Denmark, Thailand, United States
Denmark, Thailand, United States
แหล่งทุนวิจัย: Chulalongkorn University (RSA6280026)
บทคัดย่อ (Abstract): Signaling through stimulator of interferon genes (STING) leads to the production of type I interferons (IFN-Is) and inflammatory cytokines. A gain-of-function mutation in STING was identified in an autoinflammatory disease (STING-associated vasculopathy with onset in infancy; SAVI). The expressio...
Deficiency of STING Promotes Collagen-Specific Antibody Production and B Cell Survival in Collagen-Induced Arthritis
Frontiers in Immunology (2020)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Chulalongkorn University (CF_61004)
บทคัดย่อ (Abstract): The levels of interferon-alpha are high in the serum and synovial fluid of rheumatoid arthritis (RA) patients. Activation of the stimulator of type I interferon genes (STING) mediates the productions of type I interferon and promotes chronic inflammation. STING plays a significant role in autoimm...
Increased susceptibility against Cryptococcus neoformans of lupus mouse models (pristane-induction and FcGRIIb deficiency) is associated with activated macrophage, regardless of genetic background
Journal of Microbiology (2019)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Chulalongkorn University (760001-HR)
บทคัดย่อ (Abstract): The severity of cryptococcosis in lupus from varying genetic-backgrounds might be different due to the heterogeneity of lupus-pathogenesis. This study explored cryptococcosis in lupus mouse models of pristane-induction (normal genetic-background) and FcGRIIb deficiency (genetic defect). Because t...
Cortical Bone Loss in a Spontaneous Murine Model of Systemic Lupus Erythematosus
Calcified Tissue International (2018)
ประเทศร่วมวิจัย:
United States, Thailand
United States, Thailand
แหล่งทุนวิจัย: Chulalongkorn University (CU-57-091-IC)
บทคัดย่อ (Abstract): Patients with systemic lupus erythematosus (SLE), a chronic inflammatory disease characterized by loss of T- and B-cell tolerance to autoantigens, are at increased risk for osteoporosis and fractures. Mice deficient in Fc gamma receptor IIb (FcγRIIB) exhibit spontaneous SLE and its restoration re...
Helicobacter pylori infection increased anti-dsDNA and enhanced lupus severity in symptomatic FcγRIIb-deficient lupus mice
Frontiers in Microbiology (2018)
ประเทศร่วมวิจัย:
Thailand
Thailand
บทคัดย่อ (Abstract): The defect on Fc gamma receptor IIb (FcγRIIb), the only inhibitory FcγR, has been identified as one of the genetic factors increasing susceptibility to lupus. The prevalence of Helicobacter pylori (HP) and FcγRIIb dysfunction-polymorphisms are high among Asians, and their co-existence is possible...
The Synergy of Endotoxin and (1→3)-β-D-Glucan, from Gut Translocation, Worsens Sepsis Severity in a Lupus Model of Fc Gamma Receptor IIb-Deficient Mice
Journal of Innate Immunity (2018)
ประเทศร่วมวิจัย:
Thailand, United States
Thailand, United States
แหล่งทุนวิจัย: Chulalongkorn University (IRN59W0004)
บทคัดย่อ (Abstract): We investigated the influence of spontaneous gut leakage upon polymicrobial sepsis in a lupus model with Fc gamma receptor IIb-deficient (FcGRIIb-/-) mice aged 8 and 40 weeks, as representing asymptomatic and symptomatic lupus, respectively. Spontaneous gut leakage, determined by (i) the presence...
Effects of Carthamus tinctorius L. solvent extracts on anti-proliferation of human colon cancer (SW620 cell line) via apoptosis and the growth promotion of lymphocytes
Songklanakarin Journal of Science and Technology (2012)
ประเทศร่วมวิจัย:
Thailand
Thailand
บทคัดย่อ (Abstract): The in vitro effects of dichloromethane, methanol and hexane extracts of Carthamus tinctorius on caspase-dependent anti-tumor activity against human colon carcinoma SW620 cell lines were investigated by MTT assay, Annexin V staining and real-time RT-PCR. In addition, the immunomodulatory activity...