รศ.ดร. อัจฉราภรณ์ ดวงใจ
Assoc.Prof.Dr. Acharaporn Duangjai
สาขาการวิจัย:
Medicine · 51
Biochemistry, Genetics and Molecular Biology · 31
66
ผลงานตีพิมพ์
First: 18
|
Co: 48
1827
Citations รวม
24
h-index
ภาพรวมความเชี่ยวชาญและคุณภาพผลงานวิจัย (Research Highlights & Impact)
คุณภาพวารสาร (Quartiles)
Q1+Q2: 95%
Q1
45
Q2
18
Q3
3
Q4
0
ยึดตาม Scopus CiteScore
SDGs เชี่ยวชาญหลัก
พบ 8 เป้าหมาย
63 เรื่อง
26 เรื่อง
25 เรื่อง
จำแนกตามพจนานุกรมคำสำคัญของคณะ
ดัชนีอ้างอิงสากล (NIH RCR)
NIH iCite Benchmark
RCR เฉลี่ย
1.53
RCR สูงสุด
4.90
ได้รับการอ้างอิงสูงกว่าเกณฑ์เฉลี่ยโลก
เกณฑ์มาตรฐานโลก = 1.00 (NIH Benchmark)
เครือข่ายสากล & หัวข้อวิจัย
ประเทศร่วมวิจัยหลัก:
Malaysia (28)
China (10)
Pakistan (7)
หัวข้อวิจัยเด่น (OpenAlex):
การวิเคราะห์คลัสเตอร์สากล (OpenAlex Topics)
รายการผลงานสิ่งตีพิมพ์ (66 รายการ)
External Validation of a Simple Mortality Risk Prediction Score for Tuberculosis Patients
Journal of Health Research (2026)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Office of Disease Prevention (5017/2567)
บทคัดย่อ (Abstract): Background: Tuberculosis (TB) remains a significant global health issue, contributing to substantial mortality annually; therefore, effective risk stratification is essential for clinical decision-making and optimal resource allocation. This study externally validates a simple mortality predictio...
Potential of Cannabidiol (CBD) to overcome extensively drug-resistant Acinetobacter baumannii
BMC Complementary Medicine and Therapies (2025)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: University of Phayao (5031/2567)
บทคัดย่อ (Abstract): Extensively drug-resistant (XDR) Acinetobacter baumannii poses a serious clinical challenge due to its resistance to nearly all available antibiotics, including carbapenems and colistin. Cannabidiol (CBD), a non-psychoactive phytochemical from Cannabis sativa L., has recently shown promising anti...
Calcium and Vitamin D Supplementation with and Without Collagen on Bone Density and Skin Elasticity in Menopausal Women—A Randomized Controlled Study
Clinics and Practice (2025)
ประเทศร่วมวิจัย:
Thailand
Thailand
บทคัดย่อ (Abstract): Background/objectivesMenopause leads to estrogen deficiency, which negatively affects bone density, skin integrity, and hair health in women. This study aimed to evaluate the effects of fish-derived collagen peptides, calcium, and vitamin D3 supplementation on body composition, bone turnover mark...
Identification of Novel Piperidine and Pyrrolidine Derivatives as Potent Inhibitors of Pancreatic Lipase-Based Molecular Docking and In Vitro Testing
Scientia Pharmaceutica (2025)
ประเทศร่วมวิจัย:
Thailand
Thailand
บทคัดย่อ (Abstract): Obesity is a major global health concern associated with increased risks of chronic diseases and mortality. Inhibiting pancreatic lipase, a key enzyme in dietary fat absorption, presents a promising therapeutic approach. This study aimed to evaluate the inhibitory potential of piperidine derivati...
Restoring Multidrug-Resistant Escherichia coli Sensitivity to Ampicillin in Combination with (−)-Epigallocatechin Gallate
Antibiotics (2024)
ประเทศร่วมวิจัย:
Japan,
Thailand
Japan,
Thailand
แหล่งทุนวิจัย: University of Phayao (5031/2567)
บทคัดย่อ (Abstract): Multidrug-resistant (MDR) bacteria, especially Escherichia coli, are a major contributor to healthcare-associated infections globally, posing significant treatment challenges. This study explores the efficacy of (-)-epigallocatechin gallate (EGCG), a natural constituent of green tea, in combinati...
Antispasmodic Activity of Light-Roasted Coffee Extract and Its Potential Use in Gastrointestinal Motility Disorders
Foods (2024)
ประเทศร่วมวิจัย:
Japan,
Thailand,
Malaysia,
China
Japan,
Thailand,
Malaysia,
China
แหล่งทุนวิจัย: National Science and Technology Development Agency (UoE63004)
บทคัดย่อ (Abstract): Antispasmodic agents are crucial in managing gastrointestinal motility disorders by modulating muscle contractions and reducing symptoms like cramping and diarrhea. This study investigated the antispasmodic potential of different coffee bean extracts, including light coffee (LC), medium coffee (M...
Suppressive Effect of Coffee Leaves on Lipid Digestion and Absorption In Vitro
Foods (2024)
ประเทศร่วมวิจัย:
Thailand,
Malaysia,
China
Thailand,
Malaysia,
China
บทคัดย่อ (Abstract): BackgroundCoffee leaves are a major source of bioactive components and are used as ethnomedicine. However, despite their traditional medicinal use, information about their effects on antihyperlipidemia remains limited.MethodsThe aims of this study were to evaluate the main components of leaf extr...
A Promising Functional Food for Diabetes Prevention, Antioxidation, and Anti-inflammation of Green Coffee Bean Extract
Journal of Human Earth and Future (2024)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Thailand Science Research and Innovation (FF65-UOE65001)
บทคัดย่อ (Abstract): Functional foods and nutrition have become increasingly popular in preventing and reducing the incidence of diabetes. Green coffee bean extract (GCBE) has received much interest because of the evidence that coffee consumption reduces the risk of diabetes and many inflammatory diseases. This study...
Purple Eggplant (Solanum melongena L.) Ameliorates D-Galactose-Induced Cognitive Impairment Through Inhibition of Oxidative Stress and Acetylcholinesterase in the Hippocampus of an Aging Rat Model
Trends in Sciences (2024)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: University of Phayao (FF65-RIM115)
บทคัดย่อ (Abstract): The induction of neurotoxicity by d-galactose (D-Gal) is a widely recognized model that is utilized for investigating the process of aging and the associated cognitive impairment, as well as oxidative damage and cholinergic dysfunction. Eggplant fruit is a highly consumed vegetable owing to its h...
Chlorogenic acid in green bean coffee on body weight: a systematic review and meta-analysis of randomized controlled trials
Systematic Reviews (2023)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: University of Phayao (UoE63004)
บทคัดย่อ (Abstract): BackgroundSupplemental green bean coffee extract (GBCE) with caffeine has been shown to prevent weight gain. There are different dosages of GBCE that contain chlorogenic acid (CGA), and the data for their effectiveness in preventing weight gain (500 mg/day) is currently out of date. To better und...
Restoring Ampicillin Sensitivity in Multidrug-Resistant Escherichia coli Following Treatment in Combination with Coffee Pulp Extracts
Journal of Microbiology and Biotechnology (2023)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: University of Phayao (UoE65001)
บทคัดย่อ (Abstract): Escherichia coli, particularly multidrug-resistant (MDR) strains, is a serious cause of healthcare-associated infections. Development of novel antimicrobial agents or restoration of drug efficiency is required to treat MDR bacteria, and the use of natural products to solve this problem is promisi...
Synthesis and potential antidiabetic and lipid-lowering activities of putative asperidine B and its desmethyl analogue
Bioorganic and Medicinal Chemistry Letters (2023)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: National Science and Technology Development Agency (B05F640169)
บทคัดย่อ (Abstract): Putative asperidine B is an unnatural 2,6-disubstituted piperidin-3-ol and a structural isomer of (+)-preussin, a well-known pyrrolidin-3-ol alkaloid. This work reports the first enantioselective synthesis of putative asperidine B and its desmethyl analogue via a chiron approach starting from d-i...
Association of abdominal obesity and systolic blood pressure indices with cardiovascular disease risk prediction among communitydwelling older adults
Electronic Journal of General Medicine (2023)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: University of Phayao (RSC63004)
บทคัดย่อ (Abstract): Background: Excess adiposity is an established risk factor for cardiovascular disease (CVD), therefore the early screening indies with predicted CVD risk is more useful for older adults. The current study evaluated the associations between anthropometric, body composition and dietary indices and ...
Chlorogenic acid rich in coffee pulp extract suppresses inflammatory status by inhibiting the p38, MAPK, and NF-κB pathways
Heliyon (2023)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: University of Phayao (UoE63004)
บทคัดย่อ (Abstract): Coffee pulp (CP) is a coffee byproduct that contains various active ingredients, namely, chlorogenic acid (CGA) and caffeine. These active compounds show several benefits, including antihyperlipidemia, antioxidants, and anti-inflammation. However, the anti-inflammatory properties of Coffea pulp e...
Proximate composition and sensory attributes of gluten-free pasta made from jackfruit seeds
Functional Foods in Health and Disease (2023)
ประเทศร่วมวิจัย:
Thailand
Thailand
บทคัดย่อ (Abstract): Background:Pasta is the world’s favourite food, except among those with celiac disease and other gluten sensitivities. Jackfruit seeds are a good source of nutrients and are gluten-free. Replacing wheat flour with jackfruit seeds in pasta represents a potential alternative food for those with glu...
Dinactin: A New Antitumor Antibiotic with Cell Cycle Progression and Cancer Stemness Inhibiting Activities in Lung Cancer
Antibiotics (2022)
ประเทศร่วมวิจัย:
Thailand,
Brazil
Thailand,
Brazil
แหล่งทุนวิจัย: Otago School of Medical Sciences (FF64-RIM030)
บทคัดย่อ (Abstract): Lung cancer, especially non-small cell lung cancer (NSCLC), is one of the most complex diseases, despite the existence of effective treatments such as chemotherapy and immunotherapy. Since cancer stem cells (CSCs) are responsible for chemo- and radio-resistance, metastasis, and cancer recurrence,...
Botanical aspects, phytochemicals, and toxicity of Tamarindus indica leaf and a systematic review of antioxidant capacities of T. indica leaf extracts
Frontiers in Nutrition (2022)
ประเทศร่วมวิจัย:
Thailand
Thailand
บทคัดย่อ (Abstract): Oxidative stress is a condition occurs when there is the imbalance between prooxidants and free radicals. It involves in cellular metabolism, aging, and immune response. Recently oxidative stress has been proved about its beneficial roles in human body. However, long term oxidative stress and hig...
Antibacterial Activity of Coffea robusta Leaf Extract against Foodborne Pathogens
Journal of Microbiology and Biotechnology (2022)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: University of Phayao (FF65-UoE63004)
บทคัดย่อ (Abstract): The purpose of this study was to examine the phytochemical compounds and antibacterial activity of Coffea robusta leaf extract (RLE). The results indicated that chlorogenic acid (CGA) is a major component of RLE. The minimum inhibitory concentrations (MICs) of RLE against Staphylococcus aureus, B...
Cholesterol-Lowering Effects of Asperidine B, a Pyrrolidine Derivative from the Soil-Derived Fungus Aspergillus sclerotiorum PSU-RSPG178: A Potential Cholesterol Absorption Inhibitor
Pharmaceuticals (2022)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: National Science and Technology Development Agency (B05F640169)
บทคัดย่อ (Abstract): Isolated secondary metabolites asperidine B (preussin) and asperidine C, produced by the soil-derived fungus Aspergillus sclerotiorum PSU-RSPG178, were found to exhibit inhibitory effects against 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase and oxidative stress in an in vitro assay. Whether o...
Anticancer Activities of Polygonum odoratum Lour.: A Systematic Review
Frontiers in Pharmacology (2022)
ประเทศร่วมวิจัย:
Thailand
Thailand
บทคัดย่อ (Abstract): Cancers are a potential cause of death worldwide and represent a massive burden for healthcare systems. Treating cancers requires substantial resources, including skilled personnel, medications, instruments, and funds. Thus, developing cancer prevention and treatment measures is necessary for hea...
Potential Antimicrobial Properties of Coffee Beans and Coffee By-Products Against Drug-Resistant Vibrio cholerae
Frontiers in Nutrition (2022)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: University of Phayao (FF64-UoE64002)
บทคัดย่อ (Abstract): Vibrio cholerae is the causative organism of the cholera epidemic, and it remains a serious global health problem, particularly the multidrug-resistant strain, despite the development of several generic drugs and vaccines over time. Natural products have long been exploited for the treatment of v...
Antimicrobial Activity of the Green Tea Polyphenol (−)-Epigallocatechin-3-Gallate (EGCG) against Clinical Isolates of Multidrug-Resistant Vibrio cholerae
Antibiotics (2022)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: University of Phayao (621003)
บทคัดย่อ (Abstract): The spread of multidrug-resistant (MDR) Vibrio cholerae necessitates the development of novel prevention and treatment strategies. This study aims to evaluate the in vitro antibacterial activity of green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) against MDR V. cholerae. First, MIC and ...
Impact of Pharmacist-Led Diabetes Self-Care Education on Patients With Type 2 Diabetes in Pakistan: A Randomized Controlled Trial
Frontiers in Pharmacology (2022)
ประเทศร่วมวิจัย:
Pakistan,
Thailand,
Malaysia,
China
Pakistan,
Thailand,
Malaysia,
China
แหล่งทุนวิจัย: University of Phayao (FF65-UoE005)
บทคัดย่อ (Abstract): Introduction: There is a little evidence on efficacy of pharmacy-based interventions on clinical outcomes of type 2 diabetes mellitus (T2DM) patients in Pakistan. Objective: To appraise the impact of pharmacist-led self-care education on glycemic control, self-care practices and disease knowledge...
Novel clinical risk scoring model for predicting mortality in patients with necrotizing fasciitis: The MNF scoring system
Medicine United States (2021)
ประเทศร่วมวิจัย:
Malaysia,
Thailand
Malaysia,
Thailand
บทคัดย่อ (Abstract): AbstractNecrotizing fasciitis (NF) is a life-threatening soft tissue infection that rapidly progresses and requires urgent surgery and medical therapy. If treatment is delayed, the likelihood of an unfavorable outcome, including death, is significantly increased. The goal of this study was to dev...
Mitigation of Environmental Stress-Impacts in Plants: Role of Sole and Combinatory Exogenous Application of Glutathione
Frontiers in Plant Science (2021)
ประเทศร่วมวิจัย:
Malaysia,
Turkey,
Thailand,
China
Malaysia,
Turkey,
Thailand,
China
แหล่งทุนวิจัย: Office of the Higher Education Commission
บทคัดย่อ (Abstract): Glutathione (GSH; γ-glutamyl-cysteinyl-glycine), a low-molecular-weight thiol, is the most pivotal metabolite involved in the antioxidative defense system of plants. The modulation of GSH on the plant in response to environmental stresses could be illustrated through key pathways such as reactive...
Coffee Consumption and Non-alcoholic Fatty Liver Disease: An Umbrella Review and a Systematic Review and Meta-analysis
Frontiers in Pharmacology (2021)
ประเทศร่วมวิจัย:
Thailand,
United States,
Malaysia
Thailand,
United States,
Malaysia
แหล่งทุนวิจัย: University of Phayao (FF65-UoE005)
บทคัดย่อ (Abstract): Background: The effects of coffee consumption on hepatic outcomes are controversial. This study investigated the associations between coffee consumption and the incidence of non-alcoholic fatty liver disease (NAFLD) in the general population and the reduction of liver fibrosis among patients with...
Novel Clinical Risk Scoring Model for Predicting Amputation in Patients With Necrotizing Fasciitis: The ANF Risk Scoring System
Frontiers in Medicine (2021)
ประเทศร่วมวิจัย:
Thailand,
Malaysia
Thailand,
Malaysia
แหล่งทุนวิจัย: University of Phayao
บทคัดย่อ (Abstract): Background: Necrotizing fasciitis (NF) is a life-threatening infection of the skin and soft tissue that spreads quickly and requires immediate surgery and medical treatment. Amputation or radical debridement of necrotic tissue is generally always required. The risks and benefits of both the surgi...
Coffea arabica pulp aqueous extract attenuates oxidative stress and hepatic lipid accumulation in HepG2 cells
Journal of Herbal Medicine (2021)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Chiang Mai University (66/2560)
บทคัดย่อ (Abstract): Coffea arabica pulp aqueous extract (CPE) contains several bioactive compounds including chlorogenic acid (CGA), caffeine, catechin and epicatechin. These constituents exhibit several biological activities including antibacterial, anti-inflammatory, antioxidant, and lipid-lowering activities. The...
Antispasmodic effect of asperidine b, a pyrrolidine derivative, through inhibition of l-type ca2+ channel in rat ileal smooth muscle
Molecules (2021)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: National Science and Technology Development Agency (UoE64002)
บทคัดย่อ (Abstract): Antispasmodic agents are used for modulating gastrointestinal motility. Several compounds isolated from terrestrial plants have antispasmodic properties. This study aimed to explore the inhibitory effect of the pyrrolidine derivative, asperidine B, isolated from the soil-derived fungus Aspergillu...
Shifting of Physicochemical and Biological Characteristics of Coffee Roasting Under Ultrasound-Assisted Extraction
Frontiers in Nutrition (2021)
ประเทศร่วมวิจัย:
Thailand,
Malaysia,
China
Thailand,
Malaysia,
China
แหล่งทุนวิจัย: Office of the Higher Education Commission (FF64-UoE003)
บทคัดย่อ (Abstract): Ultrasound-assisted extraction (UAE) is an effective tool for the extraction of natural antioxidants. Thus, differentially roasted Arabica-coffee beans known as light (LC), medium (MC), and dark coffee (DC) were prepared and extracted under the influence of UAE. Following that, they were examined...
Harnessing the potential of CRISPR/Cas in atherosclerosis: Disease modeling and therapeutic applications
International Journal of Molecular Sciences (2021)
ประเทศร่วมวิจัย:
Malaysia,
Australia,
Thailand,
China,
Italy
Malaysia,
Australia,
Thailand,
China,
Italy
แหล่งทุนวิจัย: Ministry of Higher Education, Malaysia (FRGS/1/2019/SKK08/TAYLOR/02/2)
บทคัดย่อ (Abstract): Atherosclerosis represents one of the major causes of death globally. The high mortality rates and limitations of current therapeutic modalities have urged researchers to explore potential alternative therapies. The clustered regularly interspaced short palindromic repeats-associated protein 9 (C...
Coffea arabica bean extract inhibits glucose transport and disaccharidase activity in caco-2 cells
Biomedical Reports (2021)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: University of Phayao (FF64‑RIB008)
บทคัดย่อ (Abstract): The major constituents of Coffea arabica (coffee), including caffeine, chlorogenic acid and caffeic acid, exhibit antihyperglycemic properties in in vitro and in vivo models. However, whether Coffea arabica bean extract (CBE) regulates glucose uptake activity and the underlying mechanisms involve...
Anti-influenza with green tea catechins: A systematic review and meta-analysis
Molecules (2021)
ประเทศร่วมวิจัย:
Malaysia,
Thailand
Malaysia,
Thailand
แหล่งทุนวิจัย: University of Phayao (FF64‐UoE003)
บทคัดย่อ (Abstract): Influenza is one of the most serious respiratory viral infections worldwide. Although several studies have reported that green tea catechins (GTCs) might prevent influenza virus infection, this remains controversial. We performed a systematic review and meta-analysis of eight studies with 5,048 p...
High-efficacy α,β-dehydromonacolin s improves hepatic steatosis and suppresses gluconeogenesis pathway in high-fat diet-induced obese rats
Pharmaceuticals (2021)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: National Science and Technology Development Agency (RSA5980009)
บทคัดย่อ (Abstract): Isolated α,β-dehydromonacolin S (C5) from soil-derived fungus Aspergillus sclerotiorum PSU-RSPG178 was recently shown to exhibit an inhibitory effect against 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) activity in vitro. In this study, we investigated the effects of C5 on lipid-lowerin...
Antidiabetic and renoprotective effects of Coffea arabica pulp aqueous extract through preserving organic cation transport system mediated oxidative stress pathway in experimental type 2 diabetic rats
Molecules (2021)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: National Science and Technology Development Agency (116/2559)
บทคัดย่อ (Abstract): Coffea arabica pulp (CP) is a by-product of coffee processing. CP contains polyphenols that have exhibited beneficial effects, including antioxidant and lipid-lowering effects, as well as enhanced insulin sensitivity, in in vitro and in vivo models. How polyphenols, as found in CP aqueous extract...
Effect of roasting degree, extraction time, and temperature of coffee beans on anti-hyperglycaemic and anti-hyperlipidaemic activities using ultrasound-assisted extraction
Preventive Nutrition and Food Science (2021)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: National Science and Technology Development Agency (FF64-UoE003)
บทคัดย่อ (Abstract): Coffee consumption has been linked to a low risk of metabolic syndrome. However, evidence supporting its anti-hyperglycaemic and anti-hyperlipidaemic activities remain poorly defined. The ultrasound-assisted extraction (UAE) technique has been shown to achieve high yields of bioactive compounds i...
Tiliacora triandra (Colebr.) diels leaf aqueous extract inhibits hepatic glucose production in HepG2 cells and type 2 diabetic rats
Molecules (2021)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: National Science and Technology Development Agency (PHD58I0009)
บทคัดย่อ (Abstract): This study investigated the effects of Tiliacora triandra (Colebr.) Diels aqueous extract (TTE) on hepatic glucose production in hepatocellular carcinoma (HepG2) cells and type 2 diabetic (T2DM) conditions. HepG2 cells were pretreated with TTE and its major constituents found in TTE, epicatechin ...
Unraveling the Immunopathogenesis and Genetic Variants in Vasculitis Toward Development of Personalized Medicine
Frontiers in Cardiovascular Medicine (2021)
ประเทศร่วมวิจัย:
Thailand,
Malaysia,
China
Thailand,
Malaysia,
China
แหล่งทุนวิจัย: Ministry of Higher Education, Malaysia (FF64-UoE003)
บทคัดย่อ (Abstract): Leukocytoclastic vasculitis (LCV) is a systemic autoimmune disease characterized by the inflammation of the vascular endothelium. Cutaneous small vessel vasculitis (CSVV) and anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) are two examples of LCV. Advancements in genomic...
Spasmolytic effect of Acmella oleracea flowers extract on isolated rat ileum
Journal of Herbmed Pharmacology (2021)
ประเทศร่วมวิจัย:
Malaysia,
Thailand
Malaysia,
Thailand
แหล่งทุนวิจัย: National Science and Technology Development Agency (UoE62003)
บทคัดย่อ (Abstract): Introduction: Acmella oleracea has been used as a traditional medicine for the treatment of asthma, sore throat, haemorrhoids and toothache. However, whether A. oleracea has gastrointestinal functions, such as regulation of intestinal contractions, has not been fully elucidated. Therefore, the ai...
Author Correction: Streptomyces monashensis sp. nov., a novel mangrove soil actinobacterium from East Malaysia with antioxidative potential (Scientific Reports, (2019), 9, 1, (3056), 10.1038/s41598-019-39592-6)
Scientific Reports (2020)
ประเทศร่วมวิจัย:
China,
Malaysia,
Thailand,
Pakistan
China,
Malaysia,
Thailand,
Pakistan
แหล่งทุนวิจัย: UK Research and Innovation (103626)
บทคัดย่อ (Abstract): An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Assessment of Polygonum odoratum Lour. Leaf Extract on Rat's Ileum Contraction and the Mechanisms Involved
Journal of Medicinal Food (2020)
ประเทศร่วมวิจัย:
Malaysia,
Thailand
Malaysia,
Thailand
แหล่งทุนวิจัย: University of Phayao (UoE62007)
บทคัดย่อ (Abstract): Vietnamese coriander (Polygonum odoratum Lour.) is a plant native to northern Thailand. The biological activities of P. odoratum Lour. extract (POE) include antibacterial, antiviral, and expectorant. However, the effect of POE on intestinal smooth muscle motility is unclear. The aim of this study...
Impact of long-term exposure wildfire smog on respiratory health outcomes
Expert Review of Respiratory Medicine (2020)
ประเทศร่วมวิจัย:
Malaysia,
Thailand
Malaysia,
Thailand
บทคัดย่อ (Abstract): Background: Air pollution is a global problem and also linked to respiratory diseases. Wildfire smog is a major cause of air pollution in the upper northern area of Thailand. Thus, in the current study, we examined whether long-term exposure to wildfire smog induces lung function changes in a pop...
Bioprospecting of Microbes for Valuable Compounds to Mankind
Progress in Microbes and Molecular Biology (2020)
ประเทศร่วมวิจัย:
Hong Kong,
Malaysia,
Indonesia,
Thailand
Hong Kong,
Malaysia,
Indonesia,
Thailand
บทคัดย่อ (Abstract): The most biological multiplicity on this planet is almost certainly concealed in soils. Many valuable bacteria had been extensively dispersed in soils worldwide, with soils from terrestrial, desserts and Antarctic. Hence, soils become an intensively utilized ecological niche for the inhabitants t...
Screening for biological activities of spirogyra neglecta water extract
Walailak Journal of Science and Technology (2020)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: University of Phayao
บทคัดย่อ (Abstract): The freshwater green algae, S. neglecta, has been commonly used as a Northern Thai local food due to the fact that it is composed of several nutritional components. The aim of the present study was to investigate the phytochemical properties and biological activities of an S. neglecta water extra...
Acetaminophen use and risk of renal impairment: A systematic review and meta-analysis
Kidney Research and Clinical Practice (2020)
ประเทศร่วมวิจัย:
Malaysia,
Thailand
Malaysia,
Thailand
แหล่งทุนวิจัย: University of Phayao (UoE62003)
บทคัดย่อ (Abstract): BackgroundAcetaminophen is commonly used for the relief of pain and fever. Advocacy organizations recommend acetaminophen as the drug of choice in patients with kidney disease. Although some studies have suggested a risk of renal impairment after the use of acetaminophen, the effect of acetaminop...
Streptomyces monashensis sp. nov., a novel mangrove soil actinobacterium from East Malaysia with antioxidative potential
Scientific Reports (2019)
ประเทศร่วมวิจัย:
China,
Malaysia,
Thailand,
Pakistan
China,
Malaysia,
Thailand,
Pakistan
แหล่งทุนวิจัย: UK Research and Innovation (GBA-808813)
บทคัดย่อ (Abstract): A new Streptomyces species discovered from Sarawak mangrove soil is described, with the proposed name - Streptomyces monashensis sp. nov. (strain MUSC 1JT). Taxonomy status of MUSC 1JT was determined via polyphasic approach. Phylogenetic and chemotaxonomic properties of strain MUSC 1JT were in ac...
Characterisation of an extract and fractions of Azadirachta indica flower on cholesterol lowering property and intestinal motility
Natural Product Research (2019)
ประเทศร่วมวิจัย:
Malaysia,
Thailand
Malaysia,
Thailand
แหล่งทุนวิจัย: National Research Council of Thailand (RD59052)
บทคัดย่อ (Abstract): Azadirachta indica has long been used in traditional medicine. This study focused on isolation and characterisation of active ingredients in the extract, its fractions (NF-EA, NF-AQ, NF-G) and its effect on the cholesterol absorption activity. The NF-EA fraction was identified by marker compounds...
Siamese neem flower extract suppresses cholesterol absorption by interfering NPC1L1 and micellar property in vitro and in intestinal Caco-2 cells
Research in Pharmaceutical Sciences (2019)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Chiang Mai University (66/2558)
บทคัดย่อ (Abstract): Siamese neem (Azadirachta indica A. Juss var. siamensis Valeton) (A. indica) leaf extract, a traditional ayurvedic medicine, has been reported to exhibit antipyretic, antibacterial, antidyslipidemic, and antihyperglycemia effects. This study investigated the mechanism of hypocholesterolemic effec...
Hepatoprotective effect of coffee pulp aqueous extract combined with simvastatin against hepatic steatosis in high-fat diet-induced obese rats
Journal of Functional Foods (2019)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Chiang Mai University (116/2559)
บทคัดย่อ (Abstract): This study investigated the effect of coffee pulp aqueous extract (CPE) on obesity- induced hepatic steatosis in rats and the mechanism involved. Male Wistar rats were fed high-fat diet for 12 weeks and supplemented with 1000 mg/kg BW CPE or 40 mg/kg BW simvastatin or CPE combined with 20 mg/kg B...
Inhibitory effects of Tiliacora triandra (Colebr.) Diels on cholesterol absorption
Journal of Complementary and Integrative Medicine (2019)
ประเทศร่วมวิจัย:
Malaysia,
Thailand
Malaysia,
Thailand
บทคัดย่อ (Abstract): Background Natural supplements and herbal medicines have been attracted to use for managing elevated cholesterol levels. Tiliacora triandra (Colebr.) Diels (TT) or Yanang (in Thai) is commonly used as an ingredient in various types of Thai foods. In this study, we investigated the effect of metha...
Spirogyra neglecta aqueous extract attenuates lps-induced renal inflammation
Biological and Pharmaceutical Bulletin (2019)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Thailand Research Fund (RSA5980009)
บทคัดย่อ (Abstract): Spirogyra neglecta (SN), commonly named "Tao" in Thai, is a genus of filamentous green macroalgae. SN contains polyphenols such as isoquercetin, catechin, hydroquinone and kaempferol. These constituents exhibit beneficial effects including anti-oxidant, anti-gastric ulcer, anti-hyperglycaemia and...
Lipid-lowering effects of Coffea arabica pulp aqueous extract in Caco-2 cells and hypercholesterolemic rats
Phytomedicine (2019)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Chiang Mai University (66/2560)
บทคัดย่อ (Abstract): BackgroundCoffea arabica pulp (CP) is the first by-product obtained from coffee berries during coffee processing. The major constituents of CP, including chlorogenic acid, caffeine, and epicatechin exhibit anti-hyperlipidemic effects in in vitro and in vivo models. Whether Coffea arabica pulp aqu...
Relaxant effects of Azadirachta indica A. Juss var. siamensis Valeton flower extract on isolated rat ileum contractions and the mechanisms of action
Journal of Traditional and Complementary Medicine (2018)
ประเทศร่วมวิจัย:
Malaysia,
Thailand
Malaysia,
Thailand
บทคัดย่อ (Abstract): Azadirachta indica A. Juss var. siamensis Valeton or commonly known as Siamese neem is one of the most well-known plant in traditional Ayurvedic medicine. The aim of the present study was to investigate the relaxant effects of A. indica on isolated rat ileum contractions and its potential underly...
Asperidines A–C, pyrrolidine and piperidine derivatives from the soil-derived fungus Aspergillus sclerotiorum PSU-RSPG178
Bioorganic and Medicinal Chemistry (2018)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: National Science and Technology Development Agency (PHD/0031/2555)
บทคัดย่อ (Abstract): One new pyrrolidine derivative, asperidine A (1), and two new piperidine derivatives, asperidines B (2) and C (3), were isolated from the soil-derived fungus Aspergillus sclerotiorum PSU-RSPG178 together with two known alkaloids. Compound 3 possessed an unprecedented 7-oxa-1-azabicyclo[3.2.1]octa...
Potential of coffee fruit extract and quinic acid on adipogenesis and lipolysis in 3T3-L1 adipocytes
Kobe Journal of Medical Sciences (2018)
ประเทศร่วมวิจัย:
Malaysia,
Thailand
Malaysia,
Thailand
แหล่งทุนวิจัย: National Research Council of Thailand (RD60076)
บทคัดย่อ (Abstract): This study was to assess the impact of different colors of coffee fruit (green, yellow and red) on adipogenesis and/or lipolysis using 3T3-L1 adipocytes. Characterization of chemical constituents in different colors of coffee fruit extracts was determined by ESI-Q-TOF-MS. The cytotoxicity of the ...
Focused review: Cytotoxic and antioxidant potentials of mangrove-derived streptomyces
Frontiers in Microbiology (2017)
ประเทศร่วมวิจัย:
China,
Malaysia,
Pakistan,
Thailand
China,
Malaysia,
Pakistan,
Thailand
แหล่งทุนวิจัย: Kementerian Sains, Teknologi dan Inovasi (GBA-808813)
บทคัดย่อ (Abstract): Human life expectancy is rapidly increasing with an associated increasing burden of chronic diseases, such as neurodegenerative diseases and cancer. However, there is limited progress in finding effective treatment for these conditions. For this reason, members of the genus Streptomyces have been...
Streptomyces sp. MUM212 as a source of antioxidants with radical scavenging and metal chelating properties
Frontiers in Pharmacology (2017)
ประเทศร่วมวิจัย:
Saudi Arabia,
Malaysia,
Thailand,
Pakistan
Saudi Arabia,
Malaysia,
Thailand,
Pakistan
บทคัดย่อ (Abstract): Reactive oxygen species and other radicals potentially cause oxidative damage to proteins, lipids, and DNA which may ultimately lead to various complications including mutations, carcinogenesis, neurodegeneration, cardiovascular disease, aging, and inflammatory disease. Recent reports demonstrate...
Streptomyces colonosanans sp. nov., a novel actinobacterium isolated from Malaysia mangrove soil exhibiting antioxidative activity and cytotoxic potential against human colon cancer cell lines
Frontiers in Microbiology (2017)
ประเทศร่วมวิจัย:
Malaysia,
Saudi Arabia,
Pakistan,
Thailand
Malaysia,
Saudi Arabia,
Pakistan,
Thailand
บทคัดย่อ (Abstract): Streptomyces colonosanans MUSC 93JT, a novel strain isolated from mangrove forest soil located at Sarawak, Malaysia. The bacterium was noted to be Gram-positive and to form light yellow aerial and vivid yellow substrate mycelium on ISP 2 agar. The polyphasic approach was used to determine the tax...
Rhizoma coptidis: A potential cardiovascular protective agent
Frontiers in Pharmacology (2016)
ประเทศร่วมวิจัย:
Malaysia,
Pakistan,
Thailand
Malaysia,
Pakistan,
Thailand
บทคัดย่อ (Abstract): Cardiovascular diseases (CVDs) are among the leading causes of morbidity and mortality in both the developed and developing world. Rhizoma coptidis (RC), known as Huang Lian in China, is the dried rhizome of medicinal plants from the family Ranunculaceae, such as Coptis chinensis Franch, C. delto...
Insights into bacteriophage application in controlling vibrio species
Frontiers in Microbiology (2016)
ประเทศร่วมวิจัย:
Malaysia,
Thailand
Malaysia,
Thailand
บทคัดย่อ (Abstract): Bacterial infections from various organisms including Vibrio sp. pose a serious hazard to humans in many forms from clinical infection to affecting the yield of agriculture and aquaculture via infection of livestock. Vibrio sp. is one of the main foodborne pathogens causing human infection and is...
Anti-cancer properties of the naturally occurring aphrodisiacs: Icariin and its derivatives
Frontiers in Pharmacology (2016)
ประเทศร่วมวิจัย:
Malaysia,
Thailand
Malaysia,
Thailand
บทคัดย่อ (Abstract): Epimedium (family Berberidaceae), commonly known as Horny Goat Weed or Yin Yang Huo, is commonly used as a tonic, aphrodisiac, anti-rheumatic and anti-cancer agent in traditional herbal formulations in Asian countries such as China, Japan, and Korea. The major bioactive compounds present within t...
Lovastatin Analogues from the Soil-Derived Fungus Aspergillus sclerotiorum PSU-RSPG178
Journal of Natural Products (2016)
ประเทศร่วมวิจัย:
Thailand
Thailand
บทคัดย่อ (Abstract): Three new lovastatin analogues (1, 4, and 5) together with four known lovastatin derivatives, namely, lovastatin (2), α,β-dehydrolovastatin (3), α,β-dehydrodihydromonacolin K (6), and α,β-dehydro-4a,5-dihydromonacolin L (7), were isolated from the soil-derived fungus Aspergillus sclerotiorum PSU-...
Combination cytotoxicity of backbone degradable HPMA copolymer gemcitabine and platinum conjugates toward human ovarian carcinoma cells
European Journal of Pharmaceutics and Biopharmaceutics (2014)
ประเทศร่วมวิจัย:
United States,
Thailand
United States,
Thailand
แหล่งทุนวิจัย: National Institutes of Health (P30 CA042014)
บทคัดย่อ (Abstract): Multiblock, backbone degradable HPMA copolymer-drug conjugates containing gemcitabine and DACH platinum (mP-GEM and mP-DACH Pt), respectively were synthesized by reversible addition-fragmentation chain transfer (RAFT) polymerization and subsequent chain extension by click chemistry. Using combina...
Black pepper and piperine reduce cholesterol uptake and enhance translocation of cholesterol transporter proteins
Journal of Natural Medicines (2013)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Thailand Research Fund (MRG5180254)
บทคัดย่อ (Abstract): Black pepper (Piper nigrum L.) lowers blood lipids in vivo and inhibits cholesterol uptake in vitro, and piperine may mediate these effects. To test this, the present study aimed to compare actions of black pepper extract and piperine on (1) cholesterol uptake and efflux in Caco-2 cells, (2) the ...
Potential mechanisms of hypocholesterolaemic effect of Thai spices/dietary extracts
Natural Product Research (2011)
ประเทศร่วมวิจัย:
Thailand
Thailand
บทคัดย่อ (Abstract): Several Thai spices/dietary ingredients were previously shown to have hypocholesterolaemic effects. These studies were mostly conducted in animal models in which the mechanisms of action were not yet well-established. Therefore, this study aimed to investigate the potential mechanism of hypochole...
Sericin reduces serum cholesterol in rats and cholesterol uptake into Caco-2 cells
Journal of Agricultural and Food Chemistry (2010)
ประเทศร่วมวิจัย:
Thailand
Thailand
บทคัดย่อ (Abstract): A cholesterol lowering effect of sericin was investigated both in vivo and in vitro. Rats were dosed with cholesterol with and without sericin for 14 days. Non-high-density lipoprotein (HDL) and total serum cholesterols were reduced in rats fed high-cholesterol diet with all three tested doses of...