รศ.ดร. นภาพันธ์ กังวาล
Assoc.Prof.Dr. Napapan Kangwan
สาขาการวิจัย:
Medicine · 28
Biochemistry, Genetics and Molecular Biology · 18
36
ผลงานตีพิมพ์
First: 9
|
Co: 27
615
Citations รวม
17
h-index
ภาพรวมความเชี่ยวชาญและคุณภาพผลงานวิจัย (Research Highlights & Impact)
คุณภาพวารสาร (Quartiles)
Q1+Q2: 89%
Q1
19
Q2
13
Q3
2
Q4
0
ยึดตาม Scopus CiteScore
ไม่มี Q: 2
SDGs เชี่ยวชาญหลัก
พบ 5 เป้าหมาย
35 เรื่อง
9 เรื่อง
8 เรื่อง
จำแนกตามพจนานุกรมคำสำคัญของคณะ
ดัชนีอ้างอิงสากล (NIH RCR)
NIH iCite Benchmark
RCR เฉลี่ย
1.41
RCR สูงสุด
4.33
ได้รับการอ้างอิงสูงกว่าเกณฑ์เฉลี่ยโลก
เกณฑ์มาตรฐานโลก = 1.00 (NIH Benchmark)
เครือข่ายสากล & หัวข้อวิจัย
ประเทศร่วมวิจัยหลัก:
South Korea (13)
United States (3)
Brazil (3)
หัวข้อวิจัยเด่น (OpenAlex):
การวิเคราะห์คลัสเตอร์สากล (OpenAlex Topics)
รายการผลงานสิ่งตีพิมพ์ (36 รายการ)
Blood Metabolomic Profiling of Systemic Responses to Dried Black Lychee in a Scopolamine-Induced Cognitive Impairment in Rats
Biology (2026)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Chiang Mai University (207612)
บทคัดย่อ (Abstract): Article
Protective effects of Perilla frutescens seed oil on cognitive function, oxidative stress and acetylcholinesterase activity in a D‑galactose‑induced accelerated aging model in rats
Biomedical Reports (2026)
ประเทศร่วมวิจัย:
Thailand, United States
Thailand, United States
แหล่งทุนวิจัย: Thailand Science Research and Innovation (FF66‑RIM058)
บทคัดย่อ (Abstract): Aging‑related cognitive decline is closely associated with oxidative stress, cholinergic dysfunction and hippo‑ campal vulnerability. Perilla seed oil (PSO), a functional food rich in α‑linolenic acid and antioxidant phytochemicals, may have cognitive benefits; however, its efficacy and underlyin...
Red rice bran extract attenuates oxidative stress and testicular damage in high-fat diet/streptozotocin-induced diabetic rats
Journal of Applied Pharmaceutical Science (2026)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: University of Phayao (257/2567)
บทคัดย่อ (Abstract): Type 2 diabetes (T2D) is a chronic metabolic disorder known to impair male reproductive function through mechanisms involving insulin resistance, hyperglycemia, and oxidative stress. This study aimed to investigate the potential of red rice bran extract (RBE), a dietary antioxidant, alone or in c...
Protective Role of Rosmarinic Acid–Enriched Elsholtzia kachinensis Extract Against Oxidative and Inflammatory Stress in Human Trophoblasts Through the miR-138-5p/FOXC1 Pathway
Biochemistry Research International (2026)
ประเทศร่วมวิจัย:
Thailand, Brazil
Thailand, Brazil
แหล่งทุนวิจัย: Thailand Science Research and Innovation (N42A660433)
บทคัดย่อ (Abstract): Inflammation-induced dysregulation of microRNAs, particularly miR-138-5p, compromises trophoblast cell function and may contribute to pregnancy-related complications. While Elsholtzia species have been reported to possess therapeutic properties, the anti-inflammatory effects of Elsholtzia kachine...
MicroRNA expression in response to environmental hazards: Implications for health
Ecotoxicology and Environmental Safety (2025)
ประเทศร่วมวิจัย:
Thailand, Brazil
Thailand, Brazil
แหล่งทุนวิจัย: Thailand Science Research and Innovation (N42A660433)
บทคัดย่อ (Abstract): MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression post-transcriptionally and are increasingly recognized as sensitive biomarkers of environmental exposure. This review explores how various environmental hazards—including radiation, air pollutants, heavy metals, pesticides...
Assessing the Antioxidant, Hepatoprotective, and Iron-Chelating Potential of Perilla frutescens Seed
Biomedicines (2025)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Thailand Science Research and Innovation (KREF186410)
บทคัดย่อ (Abstract): Background/Objectives: Iron overload is a serious condition that can increase the production of reactive oxygen species (ROS), leading to oxidative tissue damage and organ dysfunction. While current pharmaceutical drugs for iron chelation have limitations, the search for natural herbs with iron-c...
Fermented Houttuynia cordata Juice Exerts Cardioprotective Effects by Alleviating Cardiac Inflammation and Apoptosis in Rats with Lipopolysaccharide-Induced Sepsis
Nutrients (2025)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: University of Phayao (WU66206)
บทคัดย่อ (Abstract): Background/Objectives: Sepsis-induced cardiac dysfunction is a major problem that often leads to severe complications and a poor prognosis. Despite the growing awareness of its impact, effective treatment options for sepsis-induced cardiac dysfunction remain limited. To date, fermented products o...
Phytochemical Screening and In Vitro Antioxidant and Anticancer Evaluation of Stem and Leaf Extracts of Cissampelos pareira L.
Mediators of Inflammation (2025)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: University of Phayao (253/2567)
บทคัดย่อ (Abstract): This study was conducted to investigate the phytochemical constituents, antioxidant capacity, and anticancer potential of aqueous, ethanolic, and hexane extracts derived from the leaves and stems of Cissampelos pareira L. (C. pareira L.). Proximate analysis revealed that the stems contained a hig...
Cleistocalyx nervosum var. paniala mitigates oxidative stress and inflammation induced by PM10 soluble extract in trophoblast cells via miR-146a-5p
Scientific Reports (2024)
ประเทศร่วมวิจัย:
Thailand, Brazil
Thailand, Brazil
แหล่งทุนวิจัย: University of Phayao (FF66-RIM067)
บทคัดย่อ (Abstract): Air pollution poses a significant global concern, notably impacting pregnancy outcomes through mechanisms such as DNA damage, oxidative stress, inflammation, and altered miRNA expression, all of which can adversely affect trophoblast functions. Cleistocalyx nervosum var. paniala, known for its ab...
Neuroprotective effects of g-Aminobutyric acid-enriched germinated riceberry extract in cerebral ischemic reperfusion-induced cognitive impairment mice
Journal of Applied Pharmaceutical Science (2024)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: University of Phayao (631006)
บทคัดย่อ (Abstract): This study investigates the neuroprotective effects of riceberry (RB) and germinated riceberry (GRB) extracts on cognitive impairment induced by cerebral ischemia-reperfusion (IR) injury. Our findings indicate that the germination process reduces total phenolic content and total antioxidant capac...
Protective Effect of Perilla Seed Meal and Perilla Seed Extract against Dextran Sulfate Sodium-Induced Ulcerative Colitis through Suppressing Inflammatory Cytokines in Mice
Molecules (2024)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: University of Phayao (MS231004)
บทคัดย่อ (Abstract): An excessive inflammatory response of the gastrointestinal tract is recognized as one of the major contributors to ulcerative colitis (UC). Despite this, effective preventive approaches for UC remain limited. Rosmarinic acid (RA), an enriched fraction from Perilla frutescens, has been shown to ex...
Antibacterial activities of Miang extracts against selected pathogens and the potential of the tannin-free extracts in the growth inhibition of Streptococcus mutans
Plos One (2024)
ประเทศร่วมวิจัย:
Thailand, United States
Thailand, United States
บทคัดย่อ (Abstract): Bacterial pathogens have remained a major public health concern for several decades. This study investigated the antibacterial activities of Miang extracts (at non-neutral and neutral pH) against Bacillus cereus TISTR 747, Escherichia coli ATCC 22595, Salmonella enterica serovar Typhimurium TISTR...
Protective Effect of Red Rice Extract Rich in Proanthocyanidins in a Murine Colitis Model
Biomedicines (2023)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: University of Phayao (FF65-RIM117)
บทคัดย่อ (Abstract): Inflammatory bowel disease (IBD) has become a global concern. Proanthocyanidin-rich red rice extract (PRRE) has been shown to suppress the inflammatory response in cellular cultures. However, the anti-colitis effect of PRRE has never been investigated in animals. This study aimed to examine the p...
Protective Effect of Probiotics Isolated from Traditional Fermented Tea Leaves (Miang) from Northern Thailand and Role of Synbiotics in Ameliorating Experimental Ulcerative Colitis in Mice
Nutrients (2022)
ประเทศร่วมวิจัย:
Thailand, United States
Thailand, United States
แหล่งทุนวิจัย: Chiang Mai University (256101A1040061)
บทคัดย่อ (Abstract): This study aimed to investigate the protective effect of probiotics and synbiotics from traditional Thai fermented tea leaves (Miang) on dextran sulfate sodium (DSS)-induced colitis in mice, in comparison to sulfasalazine. C57BL/6 mice were treated with probiotics L. pentosus A14-6, CMY46 and syn...
Anti-aging effect of polyphenols: possibilities and challenges
Plant Bioactives as Natural Panacea Against Age Induced Diseases Nutraceuticals and Functional Lead Compounds for Drug Development (2022)
ประเทศร่วมวิจัย:
Thailand
Thailand
บทคัดย่อ (Abstract): Polyphenols are a large and diverse group of natural compounds occurring in plants. Polyphenols are chemically characterized by multiple phenol units, including flavonoids, catechins, ellagic acid, and anthocyanins. Most polyphenols can reduce the generation of free radicals, reactive oxygen spec...
Molecular mechanism of antioxidant and anti-inflammatory effects of omega-3 fatty acids in perilla seed oil and rosmarinic acid rich fraction extracted from perilla seed meal on TNF-α induced A549 lung adenocarcinoma cells
Molecules (2021)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Office of the Higher Education Commission (FF64-UoE019)
บทคัดย่อ (Abstract): Industrially, after the removal of oil from perilla seeds (PS) by screw-type compression, the large quantities of residual perilla seed meal (PSM) becomes non-valuable waste. Therefore, to increase the health value and price of PS and PSM, we focused on the biological effects of perilla seed oil ...
Anti-inflammatory effect of Perilla frutescens seed oil rich in omega-3 fatty acid on dextran sodium sulfate-induced colitis in mice
Research in Pharmaceutical Sciences (2021)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Thailand Research Fund (621009)
บทคัดย่อ (Abstract): Background and purpose: Ulcerative colitis is a chronic inflammatory bowel disease that involves diffused inflammation of the large intestine. Omega-3 fatty acid (FA) has been known to regulate the inflammatory response associated with ulcerative colitis pathogenesis. Perilla frutescens is a valu...
Perilla seed oil alleviates gut dysbiosis, intestinal inflammation and metabolic disturbance in obese-insulin-resistant rats
Nutrients (2021)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Office of the Higher Education Commission (MRG6280240)
บทคัดย่อ (Abstract): Background: High-fat diet (HFD) consumption induced gut dysbiosis, inflammation, obese-insulin resistance. Perilla seed oil (PSO) is a rich source of omega-3 polyunsaturated fatty acids with health promotional effects. However, the effects of PSO on gut microbiota/inflammation and metabolic distu...
The Innovation of Functional Foods in Asia: Iffa 2018
Asia Pacific Journal of Clinical Nutrition (2019)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: University of Phayao
บทคัดย่อ (Abstract): Functional foods (FF) are commonly consumed by Asians, and this trend has increased in recent years. Despite the reported health benefits of FF, it is necessary scrutiny and updates of the underpinning research are important. The first international conference on functional food innovation in Asi...
Rosmarinic Acid Enriched Fraction from Perilla frutescens Leaves Strongly Protects Indomethacin-Induced Gastric Ulcer in Rats
Biomed Research International (2019)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Thailand Research Fund (MRG5908128)
บทคัดย่อ (Abstract): Gastric ulcers are a common problem in upper gastrointestinal tract (GI) disorders. Nonsteroidal anti-inflammatory drugs (NSAIDs) are one of the most aggressive factors leading to inducing gastric ulcers. Natural products with lower toxicity and safety are currently sought as a potential source t...
Oligonol prevented the relapse of dextran sulfate sodium-ulcerative colitis through enhancing NRF2-mediated antioxidative defense mechanism
Journal of Physiology and Pharmacology (2018)
ประเทศร่วมวิจัย:
South Korea, Thailand
South Korea, Thailand
แหล่งทุนวิจัย: Ministry of Agriculture, Food and Rural Affairs (116015-03-1-CG000)
บทคัดย่อ (Abstract): Repeated bouts of ulcerative colitis featured troublesome course of inflammatory bowel disease leading to fatal colitis-associated cancer, which is strongly associated with oxidative stress and sustained inflammation. Since oligonol, low molecular weighted polyphenol extracted from fruit lychee, ...
Thai perilla (Perilla frutescens) leaf extract inhibits human breast cancer invasion and migration
Maejo International Journal of Science and Technology (2018)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: University of Phayao
บทคัดย่อ (Abstract): Thai perilla (Perilla frutescens), also called Nga-mon, contains a substantial quantity of bioactive substances including phenolics and flavonoids. These phytochemicals have been linked to various bioactivities of P. frutescens such as in vitro and in vivo anti-inflammatory, anti-oxidative and an...
Targeted molecular ablation of cancer stem cells for curing gastrointestinal cancers
Expert Review of Gastroenterology and Hepatology (2017)
ประเทศร่วมวิจัย:
South Korea, Thailand
South Korea, Thailand
แหล่งทุนวิจัย: Ministry of Agriculture, Food and Rural Affairs (116015-03-1-CG000)
บทคัดย่อ (Abstract): Introduction: Abundance of the ATPase-binding cassette (ABC) transporters and deranged self-renewal pathways characterize the presence of cancer stem cells (CSCs) in gastrointestinal cancers (GI cancers), which play crucial roles in tumorigenesis, chemotherapy resistance, tumor recurrence, and ca...
Anti-hyperglycaemic and anti-hyperlipidaemic effects of black and red rice in streptozotocin-induced diabetic rats
Scienceasia (2017)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: University of Phoenix
บทคัดย่อ (Abstract): Increasing numbers of diabetic patients, especially those with type II, can link their condition to changes in eating habits. Black rice and red rice are not only a source of carbohydrate but also rich sources of antioxidants, especially proanthocyanidins and anthocyanins. This study determines t...
Concerted actions of ameliorated colitis, aberrant crypt foci inhibition and 15-hydroxyprostaglandin dehydrogenase induction by sonic hedgehog inhibitor led to prevention of colitis-associated cancer
International Journal of Cancer (2016)
ประเทศร่วมวิจัย:
South Korea, Thailand
South Korea, Thailand
บทคัดย่อ (Abstract): The sonic hedgehog (Shh) signaling has been known to contribute to carcinogenesis in organ, where hedgehog exerted organogenesis and in cancers, which are developed based on mutagenic inflammation. Therefore, colitis-associated cancer (CAC) can be a good model to prove whether Shh inhibitors can ...
Dietary Intervention of Artemisia and Green Tea Extracts to Rejuvenate Helicobacter pylori-Associated Chronic Atrophic Gastritis and to Prevent Tumorigenesis
Helicobacter (2016)
ประเทศร่วมวิจัย:
South Korea, Thailand
South Korea, Thailand
บทคัดย่อ (Abstract): Object: As nonmicrobial dietary approach is capable of controlling Helicobacter pylori infection, we evaluated the efficacy of long-term dietary administration of Artemisia and/or green tea extracts on H. pylori-initiated, high-salt-promoted chronic atrophic gastritis and gastric tumorigenesis mo...
Sonic hedgehog inhibitors prevent colitis-associated cancer via orchestrated mechanisms of IL-6/gp130 inhibition, 15-PGDH induction, Bcl-2 abrogation, and tumorsphere inhibition
Oncotarget (2016)
ประเทศร่วมวิจัย:
South Korea, Thailand
South Korea, Thailand
แหล่งทุนวิจัย: Ministry of Science, ICT and Future Planning (2009-0081758)
บทคัดย่อ (Abstract): Sonic hedgehog (SHH) signaling is essential in normal development of the gastrointestinal (GI) tract, whereas aberrantly activated SHH is implicated in GI cancers because it facilitates carcinogenesis by redirecting stem cells. Since colitis-associated cancer (CAC) is associated with inflammatory...
Learning and memory enhancing effects of anthocyanin in black rice extract on cerebral ischaemia in mice
Scienceasia (2015)
ประเทศร่วมวิจัย:
Thailand
Thailand
บทคัดย่อ (Abstract): The protective effect of anthocyanins extracted from black rice against learning and memory impairment was investigated in mice. In a Morris water maze test, mice with transient cerebral ischaemia required a longer time to find the hidden platform than the sham-operated controls. Daily treatment ...
Role of proton pump inhibitors in preventing hypergastrinemia-associated carcinogenesis and in antagonizing the trophic effect of gastrin
Journal of Physiology and Pharmacology (2015)
ประเทศร่วมวิจัย:
South Korea, Thailand
South Korea, Thailand
บทคัดย่อ (Abstract): Gastrin is the main hormone stimulating gastric acid secretion, but it exerts proliferative and anti-apoptotic actions on various cancer cell types, in addition to its well-known trophic effect on enterochromaffin-like cells. As treatment with proton pump inhibitors (PPIs) increases the biosynthe...
Seizing Cancer Completely Through Specific Ablating Cancer Stem Cell: The Royal Road to Chemoquiescence
Multi Targeted Approach to Treatment of Cancer (2015)
ประเทศร่วมวิจัย:
South Korea, Thailand
South Korea, Thailand
บทคัดย่อ (Abstract): Cellular quiescence is defined with reversible nonproliferating state and featured with a low metabolic state such as decreased glycolysis, reduced translation rates, and activation of autophagy. As signal for quiescence or dormancy, reduced cell growth and biosynthesis inactivating the TOR kinas...
S-allyl cysteine alleviates nonsteroidal anti-inflammatory drug-induced gastric mucosal damages by increasing cyclooxygenase-2 inhibition, heme oxygenase-1 induction, and histone deacetylation inhibition
Journal of Gastroenterology and Hepatology Australia (2014)
ประเทศร่วมวิจัย:
South Korea, Thailand
South Korea, Thailand
บทคัดย่อ (Abstract): Background and Aim: Nonsteroidal anti-inflammatory drugs (NSAIDs), the most highly prescribed drugs in the world for the treatment of pain, inflammation, and fever, are associated with gastric mucosal damages including ulcer directly or indirectly. This study was aimed to document the preventive ...
Development of GI-safe NSAID; Progression from the bark of willow tree to modern pharmacology
Current Opinion in Pharmacology (2014)
ประเทศร่วมวิจัย:
South Korea, Thailand
South Korea, Thailand
แหล่งทุนวิจัย: Ministry of Health and Welfare (A102063)
บทคัดย่อ (Abstract): Non-steroidal anti-inflammatory drugs (NSAIDs) have been used for analgesic, anti-inflammatory and antithrombotic actions and recently for cancer prevention, but they carries a risk of major gastroduodenal damages from symptomatic ulcers to serious complications leading to fatal outcomes. Therefo...
Non-microbial approach for Helicobacter pylori as faster track to prevent gastric cancer than simple eradication
World Journal of Gastroenterology (2013)
ประเทศร่วมวิจัย:
South Korea, Thailand
South Korea, Thailand
บทคัดย่อ (Abstract): Although the International Agency for Research on Cancer declared Helicobacter pylori (H. pylori) as a definite human carcinogen in 1994, the Japanese Society for Helicobacter Research only recently (February 2013) adopted the position that H. pylori infection should be considered as an indicatio...
Anti-inflammatory and carbonic anhydrase restoring actions of yam powder (Dioscorea spp) contribute to the prevention of cysteamine-induced duodenal ulcer in a rat model
Nutrition Research (2013)
ประเทศร่วมวิจัย:
South Korea, Thailand
South Korea, Thailand
แหล่งทุนวิจัย: Ministry of Health and Welfare (A102063)
บทคัดย่อ (Abstract): Increased acid output, accompanied with a defective defense system, is considered a fundamental pathogenesis of duodenal ulcer (DU). However, relapse of DU occurs despite proton pump inhibitors and H2 receptor antagonists, hence imposing the enforcement of the defense system. Dried powder of the ...
Nonsteroidal anti-inflammatory drugs (NSAID) sparing effects of glucosamine hydrochloride through n-glycosylation inhibition; Strategy to rescue stomach from nsaid damage
Journal of Physiology and Pharmacology (2013)
ประเทศร่วมวิจัย:
South Korea, Thailand
South Korea, Thailand
บทคัดย่อ (Abstract): Gastrointestinal or cardiovascular complications limit nonsteroidal anti-inflammatory drugs (NSAID) prescription. Glucosamine hydrochloride (GS-HCl) alternatively chosen, but debates still exist in its clinical efficiency. COX-2 instability through inhibiting COX-2 N-glycosylation of GS-HCl raise...
High concentrated probiotics improve inflammatory bowel diseases better than commercial concentration of probiotics
Journal of Food and Drug Analysis (2012)
ประเทศร่วมวิจัย:
South Korea, Thailand
South Korea, Thailand
บทคัดย่อ (Abstract): The incidence of inflammatory bowel diseases has increased during recent decades in Korea as well as Asian countries. Probiotics have been clinically administered to improve intestinal inflammation in inflammatory bowel disease (IBD). In this study, we identified that higher concentrations of pro...