ดร. ศศิวิมล พรมสาร
Dr. Sasivimon promsan
สาขาการวิจัย:
Medicine · 21
Biochemistry, Genetics and Molecular Biology · 12
21
ผลงานตีพิมพ์
First: 4
|
Co: 17
347
Citations รวม
10
h-index
ภาพรวมความเชี่ยวชาญและคุณภาพผลงานวิจัย (Research Highlights & Impact)
คุณภาพวารสาร (Quartiles)
Q1+Q2: 95%
Q1
15
Q2
5
Q3
1
Q4
0
ยึดตาม Scopus CiteScore
SDGs เชี่ยวชาญหลัก
พบ 3 เป้าหมาย
21 เรื่อง
9 เรื่อง
1 เรื่อง
จำแนกตามพจนานุกรมคำสำคัญของคณะ
ดัชนีอ้างอิงสากล (NIH RCR)
NIH iCite Benchmark
RCR เฉลี่ย
1.84
RCR สูงสุด
7.24
ได้รับการอ้างอิงสูงกว่าเกณฑ์เฉลี่ยโลก
เกณฑ์มาตรฐานโลก = 1.00 (NIH Benchmark)
เครือข่ายสากล & หัวข้อวิจัย
ประเทศร่วมวิจัยหลัก:
Myanmar (3)
United States (1)
South Korea (1)
หัวข้อวิจัยเด่น (OpenAlex):
การวิเคราะห์คลัสเตอร์สากล (OpenAlex Topics)
รายการผลงานสิ่งตีพิมพ์ (21 รายการ)
Fructooligosaccharides ameliorate hepatic and renal lipid accumulation and intestinal barrier dysfunctions in a pre-diabetic rat model
Biochimica Et Biophysica Acta Molecular and Cell Biology of Lipids (2026)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: National Research Council of Thailand (N42A650306)
บทคัดย่อ (Abstract): Consumption of a high-fat diet (HFD) diet is a factor associated with several diseases including obesity and its associated complications, especially liver and kidney dysfunction via promoting derangement of lipid metabolism. It has been reported that fructooligosaccharides (FOS) improve insulin ...
Corrigendum to: “Chitosan oligosaccharide mitigates kidney injury in prediabetic rats by improving intestinal barrier and renal autophagy” (Carbohydrate Polymers, (2022), 288, C, (119405), (S0144861722003095), 10.1016/j.carbpol.2022.119405)
Carbohydrate Polymers (2026)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Thailand Science Research and Innovation
บทคัดย่อ (Abstract): The authors regret that the Funding statement in the original article was incorrect. The correct funding information is provided below: This work was supported by the National Research Council of Thailand (NRCT): NRCT5-RGJ63004-078 (PS and AL); Thailand Science Research and Innovation (TSRI) (AL)...
Chitosan oligosaccharide improves diabetic nephropathy by attenuating renal fibrogenesis and strengthening intestinal barriers in type 2 diabetic rats
Chemico Biological Interactions (2025)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Chiang Mai University (N42A650306)
บทคัดย่อ (Abstract): It has been demonstrated that systemic low-grade inflammation and renal oxidative stress induce renal complications and diabetic nephropathy (DN) in conditions associated with diabetes. Chitosan oligosaccharide (COS) has been shown to attenuate kidney injury by enhancing renal autophagy in predia...
Pyridoxine exerts antioxidant effects on kidney injury manifestations in high-fat diet-induced obese rats
Chemico Biological Interactions (2025)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Faculty of Medicine, Chiang Mai University (N42A650306)
บทคัดย่อ (Abstract): The modern diet contains a substantial level of fat which is believed to be one of the leading causes of the progression of kidney disease. Several studies have already demonstrated that consumption of a high-fat diet (HFD) induces inflammation and oxidative stress, causing activation of upstream...
Maternal obesity promotes impaired renal autophagic process and kidney injury in male offspring
International Journal of Obesity (2025)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: National Research Council of Thailand (N42A650306)
บทคัดย่อ (Abstract): Background: Obesity during pregnancy increases the risk of obesity, insulin resistance, diabetes, and the development and progression of chronic kidney disease (CKD) in later life in offspring. Impaired renal autophagic process is linked to kidney dysfunction in the setting of increased renal lip...
Agomelatine Mitigates Kidney Damage in Obese Insulin-Resistant Rats by Inhibiting Inflammation and Necroptosis via the TNF-α/NF-ĸB/p-RIPK3 Pathway
International Journal of Molecular Sciences (2025)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: National Research Council of Thailand (N42A650306)
บทคัดย่อ (Abstract): Obesity is a risk factor for chronic kidney disease. The expansion of adipose tissues in obesity induces insulin resistance and low-grade systemic inflammation, promoting kidney damage. Our previous studies have demonstrated that agomelatine (AGOM) exerts renoprotective effects in experimental mo...
Cognitive decline, Aβ pathology, and blood–brain barrier function in aged 5xFAD mice
Fluids and Barriers of the CNS (2024)
ประเทศร่วมวิจัย:
United States, Thailand
United States, Thailand
แหล่งทุนวิจัย: National Institutes of Health (2R01AG039621)
บทคัดย่อ (Abstract): Background: Patients with Alzheimer's disease (AD) develop blood–brain barrier dysfunction to varying degrees. How aging impacts Aβ pathology, blood–brain barrier function, and cognitive decline in AD remains largely unknown. In this study, we used 5xFAD mice to investigate changes in Aβ levels, ...
Fructooligosaccharides Ameliorate Renal Injury and Dysfunction Through the Modulation of Gut Dysbiosis, Inhibition of Renal Inflammation, Oxidative Stress, Fibrosis, and Improve Organic Anion Transporter 3 Function in an Obese Rat Model
Molecular Nutrition and Food Research (2024)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Functional Food Research Center for Well-being, Chiang Mai University (N42A650306)
บทคัดย่อ (Abstract): ScopeHigh-fat diet (HFD) consumption causes obesity and gut dysbiosis which induces kidney injury. It has been reported that prebiotics improve gut dysbiosis and insulin sensitivity and decelerate the progression of kidney disease. This study investigates the impact of fructooligosaccharides (FOS...
Dapagliflozin and metformin in combination ameliorates diabetic nephropathy by suppressing oxidative stress, inflammation, and apoptosis and activating autophagy in diabetic rats
Biochimica Et Biophysica Acta Molecular Basis of Disease (2024)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Chiang Mai University (N42A650306)
บทคัดย่อ (Abstract): Considering the effects of sodium-glucose cotransporter inhibitors and metformin on the kidneys, a combination of both agents is postulated to provide protection against diabetic nephropathy (DN). We examined the potential protective effects of dapagliflozin, metformin, and their combination on k...
Metformin mitigates renal dysfunction in obese insulin-resistant rats via activation of the AMPK/PPARα pathway
Archives of Pharmacal Research (2023)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Chiang Mai University (N42A650306)
บทคัดย่อ (Abstract): Insulin signaling and lipid metabolism are disrupted by long-term consumption of a high-fat diet (HFD). This disruption can lead to insulin resistance, dyslipidemia and subsequently renal dysfunction as a consequence of the inactivation of the AMP-activated protein kinase (AMPK) and peroxisome pr...
Resistant starch from black rice, Oryza sativa L. var. ameliorates renal inflammation, fibrosis and injury in insulin resistant rats
Phytotherapy Research (2023)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Chiang Mai University (N42A650306)
บทคัดย่อ (Abstract): It has recently been reported that black rice (BR) extract has anti-obesity, anti-diabetic, and anti-osteoporosis effects. It has been shown to reduce obese-related kidney dysfunction in animal models. This study aimed to investigate the effect of resistant starch from BR (RS) on renal inflammati...
Chitosan oligosaccharide mitigates kidney injury in prediabetic rats by improving intestinal barrier and renal autophagy
Carbohydrate Polymers (2022)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Chiang Mai University
บทคัดย่อ (Abstract): Consumption of a high-fat diet (HFD) not only increases the risk of metabolic syndrome but also initiates kidney injury. Lipid accumulation-induced systemic low-grade inflammation is an upstream mechanism of kidney injury associated with prediabetes. Chitosan oligosaccharide (COS) provides potent...
Agomelatine, a structural analog of melatonin, improves kidney dysfunction through regulating the AMPK/mTOR signaling pathway to promote autophagy in obese rats
Food and Chemical Toxicology (2022)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Chiang Mai University (081/2563 AL)
บทคัดย่อ (Abstract): This study aimed to investigate the renoprotective effect of agomelatine on kidney injury in an obese rat model and to understand the underlying mechanisms involving the AMPK-mTOR-autophagy signaling pathway. Male Wistar rats were fed either a normal (ND) or a high-fat diet (HF) for 16 weeks. The...
Noninvasive NMR/MRS Metabolic Parameters to Evaluate Metabolic Syndrome in Rats
Diagnostics (2022)
ประเทศร่วมวิจัย:
South Korea, Thailand, 
China, 
Singapore
South Korea, Thailand, China, Singapore
แหล่งทุนวิจัย: Chiang Mai University (R000030589)
บทคัดย่อ (Abstract): (1) Background: Ectopic fat deposition and its effects, metabolic syndrome, have been significantly correlated to lifestyle and caloric consumption. There is no specific noninvasive evaluation tool being used in order to establish clinical markers for tracing the metabolic pathway implicated in o...
The combination of dapagliflozin and statins ameliorates renal injury through attenuating the activation of inflammasome-mediated autophagy in insulin-resistant rats
Journal of Biochemical and Molecular Toxicology (2022)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Chiang Mai University
บทคัดย่อ (Abstract): Long-term use of a high-fat diet with high-fructose (HFF) intake could promote insulin resistance and induce lipid accumulation leading to kidney injury possibly via impairment of the autophagy process and enhancement of the inflammasome pathway. We investigated whether dapagliflozin as a monothe...
Anthocyanin-rich fraction from black rice, Oryza sativa L. var. indica “Luem Pua,” bran extract attenuates kidney injury induced by high-fat diet involving oxidative stress and apoptosis in obese rats
Phytotherapy Research (2021)
ประเทศร่วมวิจัย:
Thailand, Myanmar
Thailand, Myanmar
แหล่งทุนวิจัย: Chiang Mai University
บทคัดย่อ (Abstract): Obesity is acknowledged as being a world health problem and increases the risk of several chronic diseases including chronic kidney disease. High-fat diet consumption and obesity-related renal disease show a close correlation with increased oxidative stress. Black rice bran extract, (BRE) Oryza s...
Dapagliflozin ameliorates pancreatic injury and activates kidney autophagy by modulating the AMPK/mTOR signaling pathway in obese rats
Journal of Cellular Physiology (2021)
ประเทศร่วมวิจัย:
Thailand, Myanmar
Thailand, Myanmar
แหล่งทุนวิจัย: Chiang Mai University (TRF‐MRG 6280030)
บทคัดย่อ (Abstract): Chronic consumption of a high-fat diet induces obesity and impairs the ultra-structure of organs and tissues. We examined the effect of sodium-glucose cotransporter 2 (SGLT2) inhibitor-dapagliflozin on renal and pancreatic injuries in obese condition. Rats were fed a high-fat diet for 16 weeks to...
Agomelatine protects against obesity-induced renal injury by inhibiting endoplasmic reticulum stress/apoptosis pathway in rats
Toxicology and Applied Pharmacology (2021)
ประเทศร่วมวิจัย:
Thailand, Myanmar
Thailand, Myanmar
แหล่งทุนวิจัย: Chiang Mai University (156/2561 AL)
บทคัดย่อ (Abstract): Obesity is recognized as a risk for the development of chronic kidney disease. Excessive fat accumulation in obesity is associated with the overproduction of reactive oxygen species with the underproduction of antioxidant mechanisms generating oxidative stress together with chronic low-grade infl...
The roles of melatonin on kidney injury in obese and diabetic conditions
Biofactors (2020)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Chiang Mai University (PhD/0108/2561)
บทคัดย่อ (Abstract): Obesity is a common and complex health problem worldwide and can induce the development of Type 2 diabetes. Chronic kidney disease (CKD) is a complication occurring as a result of obesity and diabetic conditions that lead to an increased mortality rate. There are several mechanisms and pathways c...
Atorvastatin improves renal organic anion transporter 3 and renal function in gentamicin-induced nephrotoxicity in rats
Experimental Physiology (2016)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: National Science and Technology Development Agency (10/2559)
บทคัดย่อ (Abstract): What is the central question of this study? This study was designed to determine the renoprotective effects of atorvastatin treatment in an experimental model of gentamicin-induced nephrotoxicity through modulating the Nrf2 pathway by decreasing the oxidative stress. What is the main finding and ...
Pinocembrin attenuates gentamicin-induced nephrotoxicity in rats
Canadian Journal of Physiology and Pharmacology (2015)
ประเทศร่วมวิจัย:
Thailand
Thailand
แหล่งทุนวิจัย: Chiang Mai University (RSA5780029)
บทคัดย่อ (Abstract): Oxidative stress mediated apoptosis of renal tubular cells is a major pathology of gentamicin-induced nephrotoxicity, which is one of the prevailing causes of acute renal failure. Pinocembrin is a major flavonoid found in rhizomes of fingerroot (Boesenbergia pandurata). It has pharmacological and...