Medical Sciences Research

คณะวิทยาศาสตร์การแพทย์ มหาวิทยาลัยพะเยา
ซิงค์ข้อมูลล่าสุด: 31 ส.ค. 2569 - 14:56 น.
ย้อนกลับไปรายชื่อนักวิจัย
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ผศ.ดร. อัจฉราภรณ์ อ่อนตะวงศ์
Asst.prof. Dr. Atcharaporn Ontawong
Physiology • สายวิชาการ • atcharaporn.on@up.ac.th
สาขาการวิจัย: Medicine · 36 Biochemistry, Genetics and Molecular Biology · 22
Scopus
44
ผลงานตีพิมพ์
First: 17 | Co: 27
483
Citations รวม
14
h-index
ภาพรวมความเชี่ยวชาญและคุณภาพผลงานวิจัย (Research Highlights & Impact)
คุณภาพวารสาร (Quartiles) Q1+Q2: 98%
Q1
26
Q2
17
Q3
1
Q4
0
ยึดตาม Scopus CiteScore
SDGs เชี่ยวชาญหลัก พบ 5 เป้าหมาย
3 การมีสุขภาพและความเป็นอยู่ที่ดี
44 เรื่อง
2 ขจัดความหิวโหย
16 เรื่อง
9 อุตสาหกรรม นวัตกรรม และโครงสร้างพื้นฐาน
10 เรื่อง
จำแนกตามพจนานุกรมคำสำคัญของคณะ
ดัชนีอ้างอิงสากล (NIH RCR) NIH iCite Benchmark
RCR เฉลี่ย
1.10
RCR สูงสุด
5.31
ได้รับการอ้างอิงสูงกว่าเกณฑ์เฉลี่ยโลก
เกณฑ์มาตรฐานโลก = 1.00 (NIH Benchmark)
เครือข่ายสากล & หัวข้อวิจัย
ประเทศร่วมวิจัยหลัก:
Malaysia (4) Japan (2) China (2)
หัวข้อวิจัยเด่น (OpenAlex):
Coffee research and impacts
Natural Antidiabetic Agents Studies
การวิเคราะห์คลัสเตอร์สากล (OpenAlex Topics)
สถิติการอัปเดตผลงาน
รวม 31 ทุน
National Science and Technology Development Agency 7 ทุน
University of Phayao 6 ทุน
Chiang Mai University 4 ทุน
Maejo University 2 ทุน
Otago School of Medical Sciences 2 ทุน
Thailand Science Research and Innovation 2 ทุน
Agência Nacional de Inovação 1 ทุน
Japan Society for the Promotion of Science 1 ทุน
Mae Fah Luang University 1 ทุน
National Institutes of Health 1 ทุน
National Research Council of Thailand 1 ทุน
Office of National Higher Education Science Research and Innovation Policy Council 1 ทุน
Thailand Research Fund 1 ทุน
Thailand Toray Science Foundation 1 ทุน
นับจากเลขทุน/รหัสทุนที่ไม่ซ้ำกันต่อแหล่งทุน ผลงานหลายชิ้นจากทุนก้อนเดียวกันจะนับเป็น 1 ทุน

รายการผลงานสิ่งตีพิมพ์ (44 รายการ)

Lipid-lowering and hepatoprotective effects of Ocimum sanctum L. (Thai holy basil) flower against MASLD and liver inflammation in rats
ผู้แต่ง: Inchai J.
Food Research International (2026)
ประเทศร่วมวิจัย: Thailand
แหล่งทุนวิจัย: National Research Council of Thailand (N41A640337)
บทคัดย่อ (Abstract): Metabolic dysfunction-associated steatotic liver disease (MASLD) has been defined as the fatty liver disease associated with systemic metabolic dysregulation, lipid dysregulation, and inflammation. Although the U.S. FDA has approved semaglutide and resmetirom as the options for treatment of non-a...
scopus DOI: 10.1016/j.foodres.2026.119968 Q1 Co-Author 3 SDG 3 (95%)
Red rice bran extract attenuates oxidative stress and testicular damage in high-fat diet/streptozotocin-induced diabetic rats
ผู้แต่ง: Jeefoo W.P.
Journal of Applied Pharmaceutical Science (2026)
ประเทศร่วมวิจัย: Thailand
แหล่งทุนวิจัย: University of Phayao (257/2567)
บทคัดย่อ (Abstract): Type 2 diabetes (T2D) is a chronic metabolic disorder known to impair male reproductive function through mechanisms involving insulin resistance, hyperglycemia, and oxidative stress. This study aimed to investigate the potential of red rice bran extract (RBE), a dietary antioxidant, alone or in c...
scopus DOI: 10.7324/JAPS.2026.249609 Q2 Co-Author 3 SDG 3 (90%) 2 SDG 2 (60%)
Fructooligosaccharide supplementation alleviates obesity-related kidney injury in a high-fat diet rat model
ผู้แต่ง: Wanchai K.
Archives of Physiology and Biochemistry (2026)
ประเทศร่วมวิจัย: Thailand
บทคัดย่อ (Abstract): Kidney injury is a common complication of obesity. This study evaluated the protective effect of the prebiotic fructooligosaccharide (FOS) on kidney injury in a high-fat diet-induced obese rat model. Obese rats exhibited increased body weights, elevated lipid profiles, decreased plasma lipopolysa...
scopus DOI: 10.1080/13813455.2025.2581993 Q1 Co-Author 3 SDG 3 (95%) 2 SDG 2 (60%)
Inhibition of Intestinal Cholesterol Absorption by Ocimum sanctum L. Flower Aqueous Extract via Changing Physicochemical Properties of Cholesterol Micelles
ผู้แต่ง: Inchai J.
Journal of Food Biochemistry (2026)
ประเทศร่วมวิจัย: Thailand
แหล่งทุนวิจัย: Maejo University (N41A640337)
บทคัดย่อ (Abstract): Hyperlipidemia is recognized as a major contributor to chronic noncommunicable diseases. The primary strategy regarding hyperlipidemia prevention is involved in the blockade of intestinal cholesterol absorption. Ezetimibe (Eze) is the sole prescribed drug that targets Niemann-Pick C1 Like 1 (NPC1...
scopus DOI: 10.1155/jfbc/8639786 Q1 Co-Author 3 SDG 3 (95%)
Potential lipid-lowering effects of Coffea arabica pulp extract product in hyperlipidemia-obese subjects: a randomized double-blind placebo-controlled trial
ผู้แต่ง: Buranapin S.
Frontiers in Nutrition (2026)
ประเทศร่วมวิจัย: Thailand
บทคัดย่อ (Abstract): Background: Coffea arabica pulp aqueous extract (CPE) exhibits anti-hyperlipidemia, anti-hyperglycemia, and anti-inflammatory effects in vitro and in vivo. This randomized, double-blind, controlled study evaluated the lipid-lowering effects of the CPE product in hyperlipemia-obese participants. M...
scopus DOI: 10.3389/fnut.2026.1755054 Q1 Co-Author 3 SDG 3 (100%)
Anti-inflammatory effects and gut microbiota modulation of synbiotic mulberry in DSS-induced colitis rats
ผู้แต่ง: Ontawong A.
Molecular and Cellular Biochemistry (2025)
ประเทศร่วมวิจัย: Thailand
บทคัดย่อ (Abstract): The global incident shows that the number of inflammatory bowel disease (IBD) cases increased by 88.30% in 2021 and significantly influenced patients' quality of life. Synbiotics are recommended as an alternative or supplement for IBD. We formulated synbiotic mulberry (SM) by mixing mulberry powd...
scopus DOI: 10.1007/s11010-025-05309-9 Q1 First Author 3 SDG 3 (95%) 2 SDG 2 (46%)
Hibiscus sabdariffa L. (Roselle flower) extract exerts protective effects against lipopolysaccharide-induced inflammation by ameliorating TLR4/NF-κB and NLRP3 inflammasome activation
ผู้แต่ง: Munkong N.
Inflammopharmacology (2025)
ประเทศร่วมวิจัย: Thailand
แหล่งทุนวิจัย: Thailand Science Research and Innovation (FF66-RIM061)
บทคัดย่อ (Abstract): The phytochemical constituents of various plant extracts have shown potential in mitigating oxidative stress and inflammation. Hibiscus sabdariffa L. (HS), known as the roselle flower, has demonstrated antioxidant and anti-inflammatory effects in several models. Our study aimed to evaluate the ef...
scopus DOI: 10.1007/s10787-025-01783-1 Q1 Co-Author 3 SDG 3 (92%) 9 SDG 9 (41%)
Synbiotic mulberry ameliorates kidney injury in dextran sodium sulfate-induced colitis rats
ผู้แต่ง: Wanchai K.
Asian Pacific Journal of Tropical Biomedicine (2025)
ประเทศร่วมวิจัย: Thailand
แหล่งทุนวิจัย: Mae Fah Luang University (2023)
บทคัดย่อ (Abstract): Objective: To investigate the effect of synbiotic mulberry on kidney injury in a dextran sodium sulfate (DSS)-induced colitis model. Methods: Male Wistar rats were given drinking water containing 4% DSS for 7 days. Subsequently, the rats were treated by oral gavage with synbiotic mulberry at 250,...
scopus DOI: 10.4103/apjtb.apjtb_39_25 Q2 Co-Author 3 SDG 3 (95%)
N-Acetylcysteine Attenuates Aβ-Mediated Oxidative Stress, Blood–Brain Barrier Leakage, and Renal Dysfunction in 5xFAD Mice
ผู้แต่ง: Ontawong A.
International Journal of Molecular Sciences (2025)
ประเทศร่วมวิจัย: United States, Thailand
แหล่งทุนวิจัย: National Institutes of Health (R01AG075583)
บทคัดย่อ (Abstract): Alzheimer’s disease (AD) is characterized by amyloid-beta (Aβ) pathology and is closely linked to oxidative stress, which contributes to blood–brain barrier leakage, renal dysfunction, and cognitive decline. We investigated the effects of N-acetyl cysteine (NAC), an FDA-approved antioxidant, on o...
scopus DOI: 10.3390/ijms26094352 Q1 First Author 3 SDG 3 (100%)
Eggplant (Solanum melongena L.) extract improves glucose uptake in LPS-induced inflammation in Caco-2/macrophages co-culture model
ผู้แต่ง: Ontawong A.
Advances in Traditional Medicine (2025)
ประเทศร่วมวิจัย: Thailand
แหล่งทุนวิจัย: Thailand Science Research and Innovation (FF65-RIM105)
บทคัดย่อ (Abstract): The inflammatory bowel disease (IBD) patients have increased intestinal glucose absorption associated with hyperglycemia and diabetes mellitus. Thus, IBD treatment might minimize diabetic mellitus risk. Eggplant extract is frequently prescribed in traditional Chinese medicine and is effective aga...
scopus DOI: 10.1007/s13596-024-00806-6 Q2 First Author 3 SDG 3 (95%)
Enhancement of intestinal tight junction assembly by Coffea arabica pulp aqueous extract: mechanism of action and role of SIRT-1
ผู้แต่ง: Sukmak P.
Advances in Traditional Medicine (2025)
ประเทศร่วมวิจัย: Thailand
แหล่งทุนวิจัย: Thailand Toray Science Foundation (BCG66230008)
บทคัดย่อ (Abstract): Intestinal tight junction disruption is considered as one of key pathogenic factors of several diseases including inflammatory bowel diseases. At present, there is no FDA-approved drug targeting intestinal tight junction recovery. Coffea arabica pulp is an agricultural waste but its aqueous extra...
scopus DOI: 10.1007/s13596-025-00817-x Q2 Co-Author 3 SDG 3 (95%) 12 SDG 12 (60%)
Potential lipid-lowering effects of preussin B on inhibition of intestinal cholesterol absorption: integrative mechanisms of action and proteomic analysis
ผู้แต่ง: Ontawong A.
Frontiers in Pharmacology (2025)
ประเทศร่วมวิจัย: Thailand, Spain
บทคัดย่อ (Abstract): Introduction: Hyperlipidemia remains a significant risk factor for cardiovascular diseases and is a leading cause of death, driving the need for novel and effective cholesterol-lowering agents. Preussin (1) has recently demonstrated lipid-lowering effects by inhibiting intestinal cholesterol abso...
scopus DOI: 10.3389/fphar.2025.1708213 Q1 First Author 3 SDG 3 (95%) 9 SDG 9 (60%)
A randomized controlled clinical trial examining the effects of Cordyceps militaris beverage on the immune response in healthy adults
ผู้แต่ง: Ontawong A.
Scientific Reports (2024)
ประเทศร่วมวิจัย: Thailand
แหล่งทุนวิจัย: Agência Nacional de Inovação (PE0201-02-64-09-0208)
บทคัดย่อ (Abstract): Cordyceps militaris (L.) Link (C. militaris) contains various beneficial substances, including polysaccharides (galactomannan), nucleotides (adenosine and cordycepin), cordycepic acid, amino acids, and sterols (ergosterol and beta-sitosterol). It also contains other essential nutrients, such as p...
scopus DOI: 10.1038/s41598-024-58742-z Q1 First Author 3 SDG 3 (95%) 9 SDG 9 (60%) RCR 5.31 · เปอร์เซ็นไทล์ 93
Antispasmodic Activity of Light-Roasted Coffee Extract and Its Potential Use in Gastrointestinal Motility Disorders
ผู้แต่ง: Duangjai A.
Foods (2024)
ประเทศร่วมวิจัย: Japan, Thailand, Malaysia, China
แหล่งทุนวิจัย: National Science and Technology Development Agency (UoE63004)
บทคัดย่อ (Abstract): Antispasmodic agents are crucial in managing gastrointestinal motility disorders by modulating muscle contractions and reducing symptoms like cramping and diarrhea. This study investigated the antispasmodic potential of different coffee bean extracts, including light coffee (LC), medium coffee (M...
scopus DOI: 10.3390/foods13152307 Q1 Co-Author 3 SDG 3 (96%) 9 SDG 9 (34%) RCR 1.19 · เปอร์เซ็นไทล์ 56
Suppressive Effect of Coffee Leaves on Lipid Digestion and Absorption In Vitro
ผู้แต่ง: Sansri V.
Foods (2024)
ประเทศร่วมวิจัย: Thailand, Malaysia, China
บทคัดย่อ (Abstract): BackgroundCoffee leaves are a major source of bioactive components and are used as ethnomedicine. However, despite their traditional medicinal use, information about their effects on antihyperlipidemia remains limited.MethodsThe aims of this study were to evaluate the main components of leaf extr...
scopus DOI: 10.3390/foods13152445 Q1 Co-Author 3 SDG 3 (94%) 2 SDG 2 (41%) RCR 1.21 · เปอร์เซ็นไทล์ 57
Subchronic oral toxicity study of the synbiotic mulberry in male and female Wistar rats
ผู้แต่ง: Ontawong A.
Food and Chemical Toxicology (2024)
ประเทศร่วมวิจัย: Thailand
บทคัดย่อ (Abstract): Mulberry (Morus alba L) fruit is traditionally used in Chinese medicine and has several beneficial effects, such as hypoglycemic, hypolipidemic, and anti-oxidative effects. We previously developed the synbiotic mulberry (SM) containing probiotic Lactobacilli, prebiotic inulin, and mulberry powder...
scopus DOI: 10.1016/j.fct.2024.114843 Q1 First Author 3 SDG 3 (74%) 12 SDG 12 (41%) RCR 0.84 · เปอร์เซ็นไทล์ 44
Red rice bran aqueous extract ameliorate diabetic status by inhibiting intestinal glucose transport in high fat diet/STZ-induced diabetic rats
ผู้แต่ง: Ontawong A.
Journal of Traditional and Complementary Medicine (2024)
ประเทศร่วมวิจัย: Thailand
แหล่งทุนวิจัย: Office of National Higher Education Science Research and Innovation Policy Council (FF64-RIB008)
บทคัดย่อ (Abstract): Red rice (Oryza sativa L.) consumption has grown recently, partly due to its potential health benefits in several disease prevention. The impact of red rice bran aqueous extract (RRBE) on intestinal glucose uptake and diabetes mellitus (DM) progression has not been thoroughly investigated. This s...
scopus DOI: 10.1016/j.jtcme.2023.12.003 Q1 First Author 3 SDG 3 (95%) RCR 0.19 · เปอร์เซ็นไทล์ 12
Purple Eggplant (Solanum melongena L.) Ameliorates D-Galactose-Induced Cognitive Impairment Through Inhibition of Oxidative Stress and Acetylcholinesterase in the Hippocampus of an Aging Rat Model
ผู้แต่ง: Jeefoo W.P.
Trends in Sciences (2024)
ประเทศร่วมวิจัย: Thailand
แหล่งทุนวิจัย: University of Phayao (FF65-RIM115)
บทคัดย่อ (Abstract): The induction of neurotoxicity by d-galactose (D-Gal) is a widely recognized model that is utilized for investigating the process of aging and the associated cognitive impairment, as well as oxidative damage and cholinergic dysfunction. Eggplant fruit is a highly consumed vegetable owing to its h...
scopus DOI: 10.48048/tis.2024.7245 Q2 Co-Author 3 SDG 3 (94%) 2 SDG 2 (41%)
Cladophora glomerata Kützing extract exhibits antioxidant, anti-inflammation, and anti-nitrosative stress against impairment of renal organic anion transport in an in vivo study
ผู้แต่ง: Ontawong A.
Nutrition Research and Practice (2024)
ประเทศร่วมวิจัย: Thailand
บทคัดย่อ (Abstract): Background/objectivesCladophora glomerata extract (CGE), rich in polyphenols, was reported to exhibit antidiabetic and renoprotective effects by modulating the functions of protein kinases-mediated organic anion transporter 1 (Oat1) and 3 (Oat3) in rats with type 2 diabetes mellitus (T2DM). Never...
scopus DOI: 10.4162/nrp.2024.18.5.633 Q2 First Author 3 SDG 3 (98%) 2 SDG 2 (58%) RCR 0.23 · เปอร์เซ็นไทล์ 15
Synthesis and potential antidiabetic and lipid-lowering activities of putative asperidine B and its desmethyl analogue
ผู้แต่ง: Thongpat K.
Bioorganic and Medicinal Chemistry Letters (2023)
ประเทศร่วมวิจัย: Thailand
แหล่งทุนวิจัย: National Science and Technology Development Agency (B05F640169)
บทคัดย่อ (Abstract): Putative asperidine B is an unnatural 2,6-disubstituted piperidin-3-ol and a structural isomer of (+)-preussin, a well-known pyrrolidin-3-ol alkaloid. This work reports the first enantioselective synthesis of putative asperidine B and its desmethyl analogue via a chiron approach starting from d-i...
scopus DOI: 10.1016/j.bmcl.2023.129437 Q2 Co-Author 3 SDG 3 (98%) 2 SDG 2 (78%) RCR 0.35 · เปอร์เซ็นไทล์ 21
Interaction of buspirone and its major metabolites with human organic cation transporters
ผู้แต่ง: Jinakote M.
Fundamental and Clinical Pharmacology (2023)
ประเทศร่วมวิจัย: Japan, Thailand
แหล่งทุนวิจัย: Japan Society for the Promotion of Science (21K19348)
บทคัดย่อ (Abstract): Buspirone, a cationic drug, is an anxiolytic and antidepressant drug. However, whether buspirone and its metabolites are interacted with organic cationic transporter remains uncertain. In this study, we examined the interaction of buspirone and its major metabolites 1-(2-pyrimidinyl)piperazine (1...
scopus DOI: 10.1111/fcp.12883 Q2 Co-Author 3 SDG 3 (89%) 9 SDG 9 (61%) RCR 0.00 · เปอร์เซ็นไทล์ 0
Association of abdominal obesity and systolic blood pressure indices with cardiovascular disease risk prediction among communitydwelling older adults
ผู้แต่ง: Duangjai A.
Electronic Journal of General Medicine (2023)
ประเทศร่วมวิจัย: Thailand
แหล่งทุนวิจัย: University of Phayao (RSC63004)
บทคัดย่อ (Abstract): Background: Excess adiposity is an established risk factor for cardiovascular disease (CVD), therefore the early screening indies with predicted CVD risk is more useful for older adults. The current study evaluated the associations between anthropometric, body composition and dietary indices and ...
scopus DOI: 10.29333/ejgm/12855 Q2 Co-Author 3 SDG 3 (98%) 2 SDG 2 (61%)
Chlorogenic acid rich in coffee pulp extract suppresses inflammatory status by inhibiting the p38, MAPK, and NF-κB pathways
ผู้แต่ง: Ontawong A.
Heliyon (2023)
ประเทศร่วมวิจัย: Thailand
แหล่งทุนวิจัย: University of Phayao (UoE63004)
บทคัดย่อ (Abstract): Coffee pulp (CP) is a coffee byproduct that contains various active ingredients, namely, chlorogenic acid (CGA) and caffeine. These active compounds show several benefits, including antihyperlipidemia, antioxidants, and anti-inflammation. However, the anti-inflammatory properties of Coffea pulp e...
scopus DOI: 10.1016/j.heliyon.2023.e13917 Q1 First Author 3 SDG 3 (91%) 12 SDG 12 (74%) RCR 3.99 · เปอร์เซ็นไทล์ 89
Antibacterial Activity of Coffea robusta Leaf Extract against Foodborne Pathogens
ผู้แต่ง: Yosboonruang A.
Journal of Microbiology and Biotechnology (2022)
ประเทศร่วมวิจัย: Thailand
แหล่งทุนวิจัย: University of Phayao (FF65-UoE63004)
บทคัดย่อ (Abstract): The purpose of this study was to examine the phytochemical compounds and antibacterial activity of Coffea robusta leaf extract (RLE). The results indicated that chlorogenic acid (CGA) is a major component of RLE. The minimum inhibitory concentrations (MICs) of RLE against Staphylococcus aureus, B...
scopus DOI: 10.4014/jmb.2204.04003 Q2 Co-Author 2 SDG 2 (84%) 3 SDG 3 (62%) RCR 0.94 · เปอร์เซ็นไทล์ 48
Cholesterol-Lowering Effects of Asperidine B, a Pyrrolidine Derivative from the Soil-Derived Fungus Aspergillus sclerotiorum PSU-RSPG178: A Potential Cholesterol Absorption Inhibitor
ผู้แต่ง: Ontawong A.
Pharmaceuticals (2022)
ประเทศร่วมวิจัย: Thailand
แหล่งทุนวิจัย: National Science and Technology Development Agency (B05F640169)
บทคัดย่อ (Abstract): Isolated secondary metabolites asperidine B (preussin) and asperidine C, produced by the soil-derived fungus Aspergillus sclerotiorum PSU-RSPG178, were found to exhibit inhibitory effects against 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase and oxidative stress in an in vitro assay. Whether o...
scopus DOI: 10.3390/ph15080955 Q1 First Author 3 SDG 3 (96%) 9 SDG 9 (22%) RCR 0.39 · เปอร์เซ็นไทล์ 23
Anti‐Inflammatory Effects of Red Rice Bran Extract Ameliorate Type I Interferon Production via STING Pathway
ผู้แต่ง: Onsa‐ard A.
Foods (2022)
ประเทศร่วมวิจัย: Thailand
แหล่งทุนวิจัย: Otago School of Medical Sciences (FF64‐ RIM039)
บทคัดย่อ (Abstract): Type I interferons (IFNs‐I) are inflammatory cytokines that play an essential role in the pathogenesis of inflammation and autoimmune diseases. Signaling through nucleic acid sensors causes the production of IFNs‐I. A stimulator of interferon genes (STING) is a DNA sensor that signals transductio...
scopus DOI: 10.3390/foods11111622 Q1 Co-Author 3 SDG 3 (90%) RCR 1.02 · เปอร์เซ็นไทล์ 51
Crocodile Oil Modulates Inflammation and Immune Responses in LPS-stimulated RAW 264.7 Macrophages
ผู้แต่ง: Ngernjan M.
Molecules (2022)
ประเทศร่วมวิจัย: Thailand
แหล่งทุนวิจัย: Otago School of Medical Sciences (PHD62I0008)
บทคัดย่อ (Abstract): Crocodile oil (CO) is generated from the fatty tissues of crocodiles as a by-product of commercial aquaculture. CO is extensively applied in the treatment of illnesses including asthma, emphysema, skin ulcers, and cancer, as well as wound healing. Whether CO has anti-inflammatory properties and e...
scopus DOI: 10.3390/molecules27123784 Q1 Co-Author 3 SDG 3 (95%) 12 SDG 12 (60%) RCR 0.51 · เปอร์เซ็นไทล์ 30
Coffea arabica pulp aqueous extract attenuates oxidative stress and hepatic lipid accumulation in HepG2 cells
ผู้แต่ง: Ontawong A.
Journal of Herbal Medicine (2021)
ประเทศร่วมวิจัย: Thailand
แหล่งทุนวิจัย: Chiang Mai University (66/2560)
บทคัดย่อ (Abstract): Coffea arabica pulp aqueous extract (CPE) contains several bioactive compounds including chlorogenic acid (CGA), caffeine, catechin and epicatechin. These constituents exhibit several biological activities including antibacterial, anti-inflammatory, antioxidant, and lipid-lowering activities. The...
scopus DOI: 10.1016/j.hermed.2021.100465 Q2 First Author 3 SDG 3 (93%) 12 SDG 12 (62%)
The enhancing immune response and anti-inflammatory effects of caulerpa lentillifera extract in raw 264.7 cells
ผู้แต่ง: Yoojam S.
Molecules (2021)
ประเทศร่วมวิจัย: Thailand
แหล่งทุนวิจัย: Maejo University (PHD60I0083)
บทคัดย่อ (Abstract): Background: Caulerpa lentillifera (CL) is a green seaweed, and its edible part represents added value as a functional ingredient. CL was dried and extracted for the determination of its active compounds and the evaluation of its biological activities. The major constituents of CL extract (CLE), i...
scopus DOI: 10.3390/molecules26195734 Q1 Co-Author 3 SDG 3 (95%) 2 SDG 2 (60%) RCR 1.01 · เปอร์เซ็นไทล์ 51
Coffea arabica bean extract inhibits glucose transport and disaccharidase activity in caco-2 cells
ผู้แต่ง: Ontawong A.
Biomedical Reports (2021)
ประเทศร่วมวิจัย: Thailand
แหล่งทุนวิจัย: University of Phayao (FF64‑RIB008)
บทคัดย่อ (Abstract): The major constituents of Coffea arabica (coffee), including caffeine, chlorogenic acid and caffeic acid, exhibit antihyperglycemic properties in in vitro and in vivo models. However, whether Coffea arabica bean extract (CBE) regulates glucose uptake activity and the underlying mechanisms involve...
scopus DOI: 10.3892/BR.2021.1449 Q1 First Author 3 SDG 3 (92%) 2 SDG 2 (58%) RCR 1.48 · เปอร์เซ็นไทล์ 64
High-efficacy α,β-dehydromonacolin s improves hepatic steatosis and suppresses gluconeogenesis pathway in high-fat diet-induced obese rats
ผู้แต่ง: Kaewmalee J.
Pharmaceuticals (2021)
ประเทศร่วมวิจัย: Thailand
แหล่งทุนวิจัย: National Science and Technology Development Agency (RSA5980009)
บทคัดย่อ (Abstract): Isolated α,β-dehydromonacolin S (C5) from soil-derived fungus Aspergillus sclerotiorum PSU-RSPG178 was recently shown to exhibit an inhibitory effect against 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) activity in vitro. In this study, we investigated the effects of C5 on lipid-lowerin...
scopus DOI: 10.3390/ph14040375 Q1 Co-Author 3 SDG 3 (96%) 2 SDG 2 (67%) RCR 0.29 · เปอร์เซ็นไทล์ 18
Antidiabetic and renoprotective effects of Coffea arabica pulp aqueous extract through preserving organic cation transport system mediated oxidative stress pathway in experimental type 2 diabetic rats
ผู้แต่ง: Boonphang O.
Molecules (2021)
ประเทศร่วมวิจัย: Thailand
แหล่งทุนวิจัย: National Science and Technology Development Agency (116/2559)
บทคัดย่อ (Abstract): Coffea arabica pulp (CP) is a by-product of coffee processing. CP contains polyphenols that have exhibited beneficial effects, including antioxidant and lipid-lowering effects, as well as enhanced insulin sensitivity, in in vitro and in vivo models. How polyphenols, as found in CP aqueous extract...
scopus DOI: 10.3390/molecules26071907 Q1 Co-Author 3 SDG 3 (96%) 12 SDG 12 (71%) RCR 1.53 · เปอร์เซ็นไทล์ 65
Tiliacora triandra (Colebr.) diels leaf aqueous extract inhibits hepatic glucose production in HepG2 cells and type 2 diabetic rats
ผู้แต่ง: Pasachan T.
Molecules (2021)
ประเทศร่วมวิจัย: Thailand
แหล่งทุนวิจัย: National Science and Technology Development Agency (PHD58I0009)
บทคัดย่อ (Abstract): This study investigated the effects of Tiliacora triandra (Colebr.) Diels aqueous extract (TTE) on hepatic glucose production in hepatocellular carcinoma (HepG2) cells and type 2 diabetic (T2DM) conditions. HepG2 cells were pretreated with TTE and its major constituents found in TTE, epicatechin ...
scopus DOI: 10.3390/molecules26051239 Q1 Co-Author 3 SDG 3 (98%) 2 SDG 2 (55%) RCR 1.15 · เปอร์เซ็นไทล์ 55
Spasmolytic effect of Acmella oleracea flowers extract on isolated rat ileum
ผู้แต่ง: Duangjai A.
Journal of Herbmed Pharmacology (2021)
ประเทศร่วมวิจัย: Malaysia, Thailand
แหล่งทุนวิจัย: National Science and Technology Development Agency (UoE62003)
บทคัดย่อ (Abstract): Introduction: Acmella oleracea has been used as a traditional medicine for the treatment of asthma, sore throat, haemorrhoids and toothache. However, whether A. oleracea has gastrointestinal functions, such as regulation of intestinal contractions, has not been fully elucidated. Therefore, the ai...
scopus DOI: 10.34172/jhp.2021.11 Q3 Co-Author 3 SDG 3 (81%) 2 SDG 2 (48%)
High affinity of 4-(4-(dimethylamino)styryl)-N-methylpyridinium transport for assessing organic cation drugs in hepatocellular carcinoma cells
ผู้แต่ง: Jinakote M.
Fundamental and Clinical Pharmacology (2020)
ประเทศร่วมวิจัย: Thailand
แหล่งทุนวิจัย: Chiang Mai University (2562)
บทคัดย่อ (Abstract): Human organic cation transporter 1 (hOCT1) and human organic cation transporter 3 (hOCT3) are highly expressed in hepatocytes and play important roles in cationic drug absorption, distribution, and elimination. A previous study demonstrated that downregulation of hOCT1 and hOCT3 mRNA was related ...
scopus DOI: 10.1111/fcp.12531 Q2 Co-Author 3 SDG 3 (95%) 9 SDG 9 (60%) RCR 0.21 · เปอร์เซ็นไทล์ 13
Impact of long-term exposure wildfire smog on respiratory health outcomes
ผู้แต่ง: Ontawong A.
Expert Review of Respiratory Medicine (2020)
ประเทศร่วมวิจัย: Malaysia, Thailand
บทคัดย่อ (Abstract): Background: Air pollution is a global problem and also linked to respiratory diseases. Wildfire smog is a major cause of air pollution in the upper northern area of Thailand. Thus, in the current study, we examined whether long-term exposure to wildfire smog induces lung function changes in a pop...
scopus DOI: 10.1080/17476348.2020.1740089 Q1 First Author 3 SDG 3 (98%) 13 SDG 13 (74%) RCR 1.14 · เปอร์เซ็นไทล์ 55
Impaired renal organic anion transport 1 (SLC22A6) and its regulation following acute myocardial infarction and reperfusion injury in rats
ผู้แต่ง: Sirijariyawat K.
Biochimica Et Biophysica Acta Molecular Basis of Disease (2019)
ประเทศร่วมวิจัย: Thailand
แหล่งทุนวิจัย: National Science and Technology Development Agency (RSA5980009)
บทคัดย่อ (Abstract): Acute kidney injury (AKI) is a high frequent and common complication following acute myocardial infarction (AMI). This study examined and identified the effect of AMI-induced AKI on organic anion transporter 1 (Oat1) and Oat3 transport using clinical setting of pre-renal AKI in vivo. Cardiac isch...
scopus DOI: 10.1016/j.bbadis.2019.05.013 Q2 Co-Author 3 SDG 3 (93%) 9 SDG 9 (66%) RCR 0.64 · เปอร์เซ็นไทล์ 36
Siamese neem flower extract suppresses cholesterol absorption by interfering NPC1L1 and micellar property in vitro and in intestinal Caco-2 cells
ผู้แต่ง: Duangjai A.
Research in Pharmaceutical Sciences (2019)
ประเทศร่วมวิจัย: Thailand
แหล่งทุนวิจัย: Chiang Mai University (66/2558)
บทคัดย่อ (Abstract): Siamese neem (Azadirachta indica A. Juss var. siamensis Valeton) (A. indica) leaf extract, a traditional ayurvedic medicine, has been reported to exhibit antipyretic, antibacterial, antidyslipidemic, and antihyperglycemia effects. This study investigated the mechanism of hypocholesterolemic effec...
scopus DOI: 10.4103/1735-5362.258485 Q2 Co-Author 3 SDG 3 (97%) 9 SDG 9 (24%) RCR 0.22 · เปอร์เซ็นไทล์ 14
Hepatoprotective effect of coffee pulp aqueous extract combined with simvastatin against hepatic steatosis in high-fat diet-induced obese rats
ผู้แต่ง: Ontawong A.
Journal of Functional Foods (2019)
ประเทศร่วมวิจัย: Thailand
แหล่งทุนวิจัย: Chiang Mai University (116/2559)
บทคัดย่อ (Abstract): This study investigated the effect of coffee pulp aqueous extract (CPE) on obesity- induced hepatic steatosis in rats and the mechanism involved. Male Wistar rats were fed high-fat diet for 12 weeks and supplemented with 1000 mg/kg BW CPE or 40 mg/kg BW simvastatin or CPE combined with 20 mg/kg B...
scopus DOI: 10.1016/j.jff.2019.02.011 Q1 First Author 3 SDG 3 (96%) 12 SDG 12 (62%)
Spirogyra neglecta aqueous extract attenuates lps-induced renal inflammation
ผู้แต่ง: Ontawong A.
Biological and Pharmaceutical Bulletin (2019)
ประเทศร่วมวิจัย: Thailand
แหล่งทุนวิจัย: Thailand Research Fund (RSA5980009)
บทคัดย่อ (Abstract): Spirogyra neglecta (SN), commonly named "Tao" in Thai, is a genus of filamentous green macroalgae. SN contains polyphenols such as isoquercetin, catechin, hydroquinone and kaempferol. These constituents exhibit beneficial effects including anti-oxidant, anti-gastric ulcer, anti-hyperglycaemia and...
scopus DOI: 10.1248/bpb.b19-00199 Q2 First Author 3 SDG 3 (96%) 12 SDG 12 (42%) RCR 0.17 · เปอร์เซ็นไทล์ 11
Lipid-lowering effects of Coffea arabica pulp aqueous extract in Caco-2 cells and hypercholesterolemic rats
ผู้แต่ง: Ontawong A.
Phytomedicine (2019)
ประเทศร่วมวิจัย: Thailand
แหล่งทุนวิจัย: Chiang Mai University (66/2560)
บทคัดย่อ (Abstract): BackgroundCoffea arabica pulp (CP) is the first by-product obtained from coffee berries during coffee processing. The major constituents of CP, including chlorogenic acid, caffeine, and epicatechin exhibit anti-hyperlipidemic effects in in vitro and in vivo models. Whether Coffea arabica pulp aqu...
scopus DOI: 10.1016/j.phymed.2018.06.021 Q1 First Author 3 SDG 3 (93%) 12 SDG 12 (68%) RCR 2.63 · เปอร์เซ็นไทล์ 81
Asperidines A–C, pyrrolidine and piperidine derivatives from the soil-derived fungus Aspergillus sclerotiorum PSU-RSPG178
ผู้แต่ง: Phainuphong P.
Bioorganic and Medicinal Chemistry (2018)
ประเทศร่วมวิจัย: Thailand
แหล่งทุนวิจัย: National Science and Technology Development Agency (PHD/0031/2555)
บทคัดย่อ (Abstract): One new pyrrolidine derivative, asperidine A (1), and two new piperidine derivatives, asperidines B (2) and C (3), were isolated from the soil-derived fungus Aspergillus sclerotiorum PSU-RSPG178 together with two known alkaloids. Compound 3 possessed an unprecedented 7-oxa-1-azabicyclo[3.2.1]octa...
scopus DOI: 10.1016/j.bmc.2018.07.036 Q2 Co-Author 3 SDG 3 (83%) 9 SDG 9 (41%) RCR 1.22 · เปอร์เซ็นไทล์ 57
Antidiabetic and renoprotective effects of cladophora glomerata kützing extract in experimental type 2 diabetic rats: A potential nutraceutical product for diabetic nephropathy
ผู้แต่ง: Srimaroeng C.
Journal of Diabetes Research (2015)
ประเทศร่วมวิจัย: Thailand
บทคัดย่อ (Abstract): Cladophora glomerata extract (CGE) has been shown to exhibit antigastric ulcer, anti-inflammatory, analgesic, hypotensive, and antioxidant activities. The present study investigated antidiabetic and renoprotective effects of CGE in type 2 diabetes mellitus (T2DM) rats. The rats were induced by hi...
scopus DOI: 10.1155/2015/320167 Q2 Co-Author 3 SDG 3 (98%) 2 SDG 2 (72%) RCR 0.78 · เปอร์เซ็นไทล์ 42
Antioxidant and renoprotective effects of Spirogyra neglecta (Hassall) Kützing extract in experimental type 2 diabetic rats
ผู้แต่ง: Ontawong A.
Biomed Research International (2013)
ประเทศร่วมวิจัย: Thailand
บทคัดย่อ (Abstract): Spirogyra neglecta extract (SNE) has shown antihyperglycemia and antihyperlipidemia in type 2 diabetic mellitus (T2DM) rats. This study investigated the antioxidant and renoprotective effects of SNE in T2DM rats induced by high-fat diet with low-single dose streptozotocin. T2DM rats were fed dail...
scopus DOI: 10.1155/2013/820786 Q1 First Author 3 SDG 3 (92%) 2 SDG 2 (71%) RCR 1.03 · เปอร์เซ็นไทล์ 51